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A postmortem study suggests a revision of the dual-hit hypothesis of Parkinson’s disease

The dual-hit hypothesis of Parkinson’s disease (PD) originally postulated that a neurotropic pathogen leads to formation of α-synuclein pathology in the olfactory bulb (OB) and dorsal motor nucleus of the vagus (DMV) and then invades the brain from these two entry points. Little work has been conduc...

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Detalles Bibliográficos
Autores principales: Borghammer, Per, Just, Mie Kristine, Horsager, Jacob, Skjærbæk, Casper, Raunio, Anna, Kok, Eloise H., Savola, Sara, Murayama, Shigeo, Saito, Yuko, Myllykangas, Liisa, Van Den Berge, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712280/
https://www.ncbi.nlm.nih.gov/pubmed/36450732
http://dx.doi.org/10.1038/s41531-022-00436-2