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A postmortem study suggests a revision of the dual-hit hypothesis of Parkinson’s disease
The dual-hit hypothesis of Parkinson’s disease (PD) originally postulated that a neurotropic pathogen leads to formation of α-synuclein pathology in the olfactory bulb (OB) and dorsal motor nucleus of the vagus (DMV) and then invades the brain from these two entry points. Little work has been conduc...
Autores principales: | Borghammer, Per, Just, Mie Kristine, Horsager, Jacob, Skjærbæk, Casper, Raunio, Anna, Kok, Eloise H., Savola, Sara, Murayama, Shigeo, Saito, Yuko, Myllykangas, Liisa, Van Den Berge, Nathalie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712280/ https://www.ncbi.nlm.nih.gov/pubmed/36450732 http://dx.doi.org/10.1038/s41531-022-00436-2 |
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