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Can magnetic resonance imaging replace conventional computerized tomography for follow-up of patients with testicular cancer? A systematic review

PURPOSE: Follow-up protocols for patients with testicular cancer (TC) have significantly reduced the number of cross-sectional imaging studies to reduce radiation exposure. At present, it is unclear whether magnetic resonance imaging (MRI) could replace conventional computerized tomography (CT) imag...

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Autores principales: Busch, Jonas, Schmidt, Stefanie, Albers, Peter, Heinzelbecker, Julia, Kliesch, Sabine, Lackner, Julia, Pfister, David, Ruf, Christian, Winter, Christian, Zengerling, Friedemann, Beyersdorff, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712293/
https://www.ncbi.nlm.nih.gov/pubmed/35037965
http://dx.doi.org/10.1007/s00345-022-03931-6
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author Busch, Jonas
Schmidt, Stefanie
Albers, Peter
Heinzelbecker, Julia
Kliesch, Sabine
Lackner, Julia
Pfister, David
Ruf, Christian
Winter, Christian
Zengerling, Friedemann
Beyersdorff, Dirk
author_facet Busch, Jonas
Schmidt, Stefanie
Albers, Peter
Heinzelbecker, Julia
Kliesch, Sabine
Lackner, Julia
Pfister, David
Ruf, Christian
Winter, Christian
Zengerling, Friedemann
Beyersdorff, Dirk
author_sort Busch, Jonas
collection PubMed
description PURPOSE: Follow-up protocols for patients with testicular cancer (TC) have significantly reduced the number of cross-sectional imaging studies to reduce radiation exposure. At present, it is unclear whether magnetic resonance imaging (MRI) could replace conventional computerized tomography (CT) imaging. The objective of this study is to summarize the scientific evidence on this topic and to review guideline recommendations with regard to the use of MRI. METHODS: A systematic literature review was performed searching Medline and Cochrane databases for prospective studies on patients with TC in the follow-up care (last search in February 2021). Additionally, guideline recommendations for TC were screened. Data extraction and quality assessment of included studies were performed and used for a descriptive presentation of results. RESULTS: A total of four studies including two ongoing trials were identified. Overall, the scientific evidence of prospective comparative studies is based on 102 patients. Data suggest that abdominal imaging with MRI can replace conventional CT for detection of lymph node metastasis of the retroperitoneum to spare radiation exposure and contrast media application. However, experienced radiologists are needed. Clinical guidelines are aware of the risk of diagnosis-induced secondary malignancy due to CT imaging and some have adapted their recommendations accordingly. Results of the two ongoing trials on 738 patients are expected soon to provide more reliable results on this topic. CONCLUSIONS: There is growing evidence that abdominopelvic MRI imaging can replace CT imaging during follow-up of patients with TC in order to reduce radiation exposure and diagnosis-induced secondary malignancy.
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spelling pubmed-97122932022-12-02 Can magnetic resonance imaging replace conventional computerized tomography for follow-up of patients with testicular cancer? A systematic review Busch, Jonas Schmidt, Stefanie Albers, Peter Heinzelbecker, Julia Kliesch, Sabine Lackner, Julia Pfister, David Ruf, Christian Winter, Christian Zengerling, Friedemann Beyersdorff, Dirk World J Urol Topic Paper PURPOSE: Follow-up protocols for patients with testicular cancer (TC) have significantly reduced the number of cross-sectional imaging studies to reduce radiation exposure. At present, it is unclear whether magnetic resonance imaging (MRI) could replace conventional computerized tomography (CT) imaging. The objective of this study is to summarize the scientific evidence on this topic and to review guideline recommendations with regard to the use of MRI. METHODS: A systematic literature review was performed searching Medline and Cochrane databases for prospective studies on patients with TC in the follow-up care (last search in February 2021). Additionally, guideline recommendations for TC were screened. Data extraction and quality assessment of included studies were performed and used for a descriptive presentation of results. RESULTS: A total of four studies including two ongoing trials were identified. Overall, the scientific evidence of prospective comparative studies is based on 102 patients. Data suggest that abdominal imaging with MRI can replace conventional CT for detection of lymph node metastasis of the retroperitoneum to spare radiation exposure and contrast media application. However, experienced radiologists are needed. Clinical guidelines are aware of the risk of diagnosis-induced secondary malignancy due to CT imaging and some have adapted their recommendations accordingly. Results of the two ongoing trials on 738 patients are expected soon to provide more reliable results on this topic. CONCLUSIONS: There is growing evidence that abdominopelvic MRI imaging can replace CT imaging during follow-up of patients with TC in order to reduce radiation exposure and diagnosis-induced secondary malignancy. Springer Berlin Heidelberg 2022-01-17 2022 /pmc/articles/PMC9712293/ /pubmed/35037965 http://dx.doi.org/10.1007/s00345-022-03931-6 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Topic Paper
Busch, Jonas
Schmidt, Stefanie
Albers, Peter
Heinzelbecker, Julia
Kliesch, Sabine
Lackner, Julia
Pfister, David
Ruf, Christian
Winter, Christian
Zengerling, Friedemann
Beyersdorff, Dirk
Can magnetic resonance imaging replace conventional computerized tomography for follow-up of patients with testicular cancer? A systematic review
title Can magnetic resonance imaging replace conventional computerized tomography for follow-up of patients with testicular cancer? A systematic review
title_full Can magnetic resonance imaging replace conventional computerized tomography for follow-up of patients with testicular cancer? A systematic review
title_fullStr Can magnetic resonance imaging replace conventional computerized tomography for follow-up of patients with testicular cancer? A systematic review
title_full_unstemmed Can magnetic resonance imaging replace conventional computerized tomography for follow-up of patients with testicular cancer? A systematic review
title_short Can magnetic resonance imaging replace conventional computerized tomography for follow-up of patients with testicular cancer? A systematic review
title_sort can magnetic resonance imaging replace conventional computerized tomography for follow-up of patients with testicular cancer? a systematic review
topic Topic Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712293/
https://www.ncbi.nlm.nih.gov/pubmed/35037965
http://dx.doi.org/10.1007/s00345-022-03931-6
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