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HMGB1 induces radioresistance through PI3K/AKT/ATM pathway in esophageal squamous cell carcinoma

BACKGROUND: To explore the effect of HMGB1 on the radio-sensitivity of esophageal cancer cells through regulating the PI3K/Akt/ATM pathway. METHODS AND RESULTS: We observed the expression of HMGB1 and p-ATM in biopsies of esophageal cancer patients with immunohistochemical staining. Western blot and...

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Detalles Bibliográficos
Autores principales: Zhang, Xueyuan, Zou, Naiyi, Deng, Wenzhao, Song, Chunyang, Yan, Ke, Shen, Wenbin, Zhu, Shuchai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712304/
https://www.ncbi.nlm.nih.gov/pubmed/36260180
http://dx.doi.org/10.1007/s11033-022-07989-8

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