Cargando…

Acetylation of Checkpoint suppressor 1 enhances its stability and promotes the progression of triple-negative breast cancer

Checkpoint suppressor 1 (CHES1), a transcriptional regulator, had been dysregulated in many types of malignancies including breast cancer, and its expression level is strongly associated with progression and prognosis of patients. However, the underlying regulatory mechanisms of CHES1 expression in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Zhaowei, Liu, Shuyan, Feng, Chun, Xu, Fuyi, Kong, Demin, Mi, Jia, Yang, Chunhua, Zhang, Guilong, Wei, Pengfei, Orgil, Buyan-Ochir, Bergquist, Jonas, Tian, Geng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712368/ https://www.ncbi.nlm.nih.gov/pubmed/36450706 http://dx.doi.org/10.1038/s41420-022-01269-x

Ejemplares similares

Ace2 and Tmprss2 Expressions Are Regulated by Dhx32 and Influence the Gastrointestinal Symptoms Caused by SARS-CoV-2
por: Xu, Fuyi, et al.
Publicado: (2021)

Cardiac copper content and its relationship with heart physiology: Insights based on quantitative genetic and functional analyses using BXD family mice
por: Bajpai, Akhilesh Kumar, et al.
Publicado: (2023)

Systems genetics analysis defines importance of TMEM43/LUMA for cardiac- and metabolic-related pathways
por: Gu, Qingqing, et al.
Publicado: (2022)

Expression Levels of the Tnni3k Gene in the Heart Are Highly Associated with Cardiac and Glucose Metabolism-Related Phenotypes and Functional Pathways
por: Gu, Qingqing, et al.
Publicado: (2023)

Silencing DTX3L Inhibits the Progression of Cervical Carcinoma by Regulating PI3K/AKT/mTOR Signaling Pathway
por: Hu, Wei, et al.
Publicado: (2023)

A Meta-Analysis on the Association Between TNFSF4 Polymorphisms (rs3861950 T > C and rs1234313 A > G) and Susceptibility to Coronary Artery Disease
por: Liu, Shuyan, et al.
Publicado: (2020)

Transcriptome-wide association study reveals cholesterol metabolism gene Lpl is a key regulator of cognitive dysfunction
por: Hu, Wei, et al.
Publicado: (2022)

Hippocampal Transcriptome-Wide Association Study Reveals Correlations Between Impaired Glutamatergic Synapse Pathway and Age-Related Hearing Loss in BXD-Recombinant Inbred Mice
por: Deng, Tingzhi, et al.
Publicado: (2021)

A systems genetics approach to revealing the Pdgfb molecular network of the retina
por: Li, Shasha, et al.
Publicado: (2020)

System biology analysis reveals the role of voltage‐dependent anion channel in mitochondrial dysfunction during non‐alcoholic fatty liver disease progression into hepatocellular carcinoma
por: Zhu, Yanping, et al.
Publicado: (2020)

Molecular basis for N-terminal alpha-synuclein acetylation by human NatB
por: Deng, Sunbin, et al.
Publicado: (2020)

N,N′-Diacetyl-N′-[(4-nitrophenoxy)acetyl]acetohydrazide
por: Hu, Xiao, et al.
Publicado: (2009)

Checkpoint suppressor 1 suppresses transcriptional activity of ERα and breast cancer cell proliferation via deacetylase SIRT1
por: Xu, Zhaowei, et al.
Publicado: (2018)

Immune checkpoint blockade in triple negative breast cancer influenced by B cells through myeloid-derived suppressor cells
por: Vito, Alyssa, et al.
Publicado: (2021)

KAT6A Acetylation of SMAD3 Regulates Myeloid‐Derived Suppressor Cell Recruitment, Metastasis, and Immunotherapy in Triple‐Negative Breast Cancer
por: Yu, Bo, et al.
Publicado: (2021)

KAT6A Acetylation of SMAD3 Regulates Myeloid‐Derived Suppressor Cell Recruitment, Metastasis, and Immunotherapy in Triple‐Negative Breast Cancer
por: Yu, Bo, et al.
Publicado: (2022)

Quantitative dot blot analysis (QDB), a versatile high throughput immunoblot method
por: Tian, Geng, et al.
Publicado: (2017)

Biobased Epoxy Composites Reinforced with Acetylated Corn Straw
por: Jiang, Siyu, et al.
Publicado: (2023)

Loss of BubR1 acetylation causes defects in spindle assembly checkpoint signaling and promotes tumor formation
por: Park, Inai, et al.
Publicado: (2013)

p300-mediated acetylation increased the protein stability of HIPK2 and enhanced its tumor suppressor function
por: Choi, Jong-Ryoul, et al.
Publicado: (2017)

Acetyl-CoA carboxylase 1 is a suppressor of the adipocyte thermogenic program
por: Guilherme, Adilson, et al.
Publicado: (2023)

Cell Size Checkpoint Control by the Retinoblastoma Tumor Suppressor Pathway
por: Fang, Su-Chiung, et al.
Publicado: (2006)

Tumor-suppressor Genes, Cell Cycle Regulatory Checkpoints, and the Skin
por: Velez, Ana Maria Abreu, et al.
Publicado: (2015)

Estrogen-Related Receptor α: A Significant Regulator and Promising Target in Bone Homeostasis and Bone Metastasis
por: Feng, Chun, et al.
Publicado: (2022)

Application of triple quadrupole mass spectrometry for the characterization of antibody–drug conjugates
por: Källsten, Malin, et al.
Publicado: (2019)

Identification of the regulatory mechanism of ACE2 in COVID-19–induced kidney damage with systems genetics approach
por: Yang, Xueling, et al.
Publicado: (2023)

Hyperinsulinemia promotes aberrant histone acetylation in triple-negative breast cancer
por: Senapati, Parijat, et al.
Publicado: (2019)

N‐acetyltransferase 10 promotes colon cancer progression by inhibiting ferroptosis through N4‐acetylation and stabilization of ferroptosis suppressor protein 1 (FSP1) mRNA
por: Zheng, Xiao, et al.
Publicado: (2022)

Acetyl-cinobufagin suppresses triple-negative breast cancer progression by inhibiting the STAT3 pathway
por: Qi, Yufeng, et al.
Publicado: (2023)

Suppressors of cytokine signaling: Potential immune checkpoint molecules for cancer immunotherapy
por: Chikuma, Shunsuke, et al.
Publicado: (2017)

Acetylation Modification During Autophagy and Vascular Aging
por: Sun, Jiaxing, et al.
Publicado: (2021)

The E3 ubiquitin ligase Itch regulates tumor suppressor protein RASSF5/NORE1 stability in an acetylation-dependent manner
por: Suryaraja, R, et al.
Publicado: (2013)

Checkpoint inhibitor therapy for metastatic triple-negative breast cancer
por: Heeke, Arielle L., et al.
Publicado: (2021)

Immunotherapy in triple negative breast cancer: beyond checkpoint inhibitors
por: Abdou, Yara, et al.
Publicado: (2022)

Open triple-branched stent graft applied to patient of acute type a aortic dissection with Aberrant Right Subclavian Artery
por: Guo, Changfa, et al.
Publicado: (2013)

A nanoselenium-coating biomimetic cytomembrane nanoplatform for mitochondrial targeted chemotherapy- and chemodynamic therapy through manganese and doxorubicin codelivery
por: Xiao, Jianmin, et al.
Publicado: (2021)

The Number of Stenotic Intracranial Arteries Is Independently Associated with Ischemic Stroke Severity
por: Wei, Xiaodan, et al.
Publicado: (2016)

Mitotic phosphorylation of tumor suppressor DAB2IP maintains spindle assembly checkpoint and chromosomal stability through activating PLK1-Mps1 signal pathway and stabilizing mitotic checkpoint complex
por: Yu, Lan, et al.
Publicado: (2021)

Tumor suppressor role of microRNA-1296 in triple-negative breast cancer
por: Phan, Binh, et al.
Publicado: (2016)

Optimal timing and sequence of combining stereotactic radiosurgery with immune checkpoint inhibitors in treating brain metastases: clinical evidence and mechanistic basis
por: Tian, Wentao, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_v5grnlnjdraeols36j7g7qsmak