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A multiple detection method for distinguishing gene mutations based on melting curves of extended quenching probes

Conventional PCR methods can detect only a few targets simultaneously and do not fulfill most clinical requirements, especially those for detecting plasma circulating DNA. By designing characteristic universal fluorescent probes, combining multiplex PCR with the invasive reaction, and analyzing the...

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Detalles Bibliográficos
Autores principales:	Jianping, Wang, Zipeng, Liu, Tengfei, Pan, Song, Zhang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712562/ https://www.ncbi.nlm.nih.gov/pubmed/36468116 http://dx.doi.org/10.1016/j.heliyon.2022.e11856

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