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Dietary curcumin supplementation enhances intestinal immunity and gill protection in juvenile greater amberjack (Seriola dumerili)
A 8-week feeding trial was conducted to determine the effects of dietary supplementation with curcumin on growth, intestinal health, and gills resistance to ammonia stress in juvenile Seriola dumerili. Three isonitrogenous and isolipidic test diets were prepared by supplementing incremental levels o...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712565/ https://www.ncbi.nlm.nih.gov/pubmed/36468091 http://dx.doi.org/10.1016/j.heliyon.2022.e11887 |
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author | He, Yuhang Fu, Zhengyi Dai, Shiming Yu, Gang Ma, Zhenhua Wang, Xiaomei |
author_facet | He, Yuhang Fu, Zhengyi Dai, Shiming Yu, Gang Ma, Zhenhua Wang, Xiaomei |
author_sort | He, Yuhang |
collection | PubMed |
description | A 8-week feeding trial was conducted to determine the effects of dietary supplementation with curcumin on growth, intestinal health, and gills resistance to ammonia stress in juvenile Seriola dumerili. Three isonitrogenous and isolipidic test diets were prepared by supplementing incremental levels of dietary curcumin at 0% (CUR0%, control), 0.01% (CUR0.01%), 0.02% (CUR0.02%), respectively. Fish were fed with experimental diet. Recovery and protection capacity after ammonia challenge assay was adopted to test the effect of curcumin. At the end of the feeding trial, the results showed that dietary supplementation with proper curcumin level had a significant positive effect on fish survival and intestinal histology structure. Meanwhile, dietary supplementation with proper curcumin level can improve intestinal health by increasing immune enzyme activity, up-regulating the expression of anti-inflammatory cytokines, down-regulating the expression of pro-inflammatory cytokines and regulating other immune-related genes. Subsequently, after the ammonia challenge and recovery experiment, the results of antioxidant-related genes and antioxidant enzymes showed that dietary supplementation with proper curcumin level can improve the gill protective and recovery capacity from ammonia stress through increasing antioxidant capacity. These results suggest that dietary supplementation with proper curcumin can promote the growth, intestinal health, gill resistance and recovery to ammonia stress of S. dumerili. |
format | Online Article Text |
id | pubmed-9712565 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-97125652022-12-02 Dietary curcumin supplementation enhances intestinal immunity and gill protection in juvenile greater amberjack (Seriola dumerili) He, Yuhang Fu, Zhengyi Dai, Shiming Yu, Gang Ma, Zhenhua Wang, Xiaomei Heliyon Research Article A 8-week feeding trial was conducted to determine the effects of dietary supplementation with curcumin on growth, intestinal health, and gills resistance to ammonia stress in juvenile Seriola dumerili. Three isonitrogenous and isolipidic test diets were prepared by supplementing incremental levels of dietary curcumin at 0% (CUR0%, control), 0.01% (CUR0.01%), 0.02% (CUR0.02%), respectively. Fish were fed with experimental diet. Recovery and protection capacity after ammonia challenge assay was adopted to test the effect of curcumin. At the end of the feeding trial, the results showed that dietary supplementation with proper curcumin level had a significant positive effect on fish survival and intestinal histology structure. Meanwhile, dietary supplementation with proper curcumin level can improve intestinal health by increasing immune enzyme activity, up-regulating the expression of anti-inflammatory cytokines, down-regulating the expression of pro-inflammatory cytokines and regulating other immune-related genes. Subsequently, after the ammonia challenge and recovery experiment, the results of antioxidant-related genes and antioxidant enzymes showed that dietary supplementation with proper curcumin level can improve the gill protective and recovery capacity from ammonia stress through increasing antioxidant capacity. These results suggest that dietary supplementation with proper curcumin can promote the growth, intestinal health, gill resistance and recovery to ammonia stress of S. dumerili. Elsevier 2022-11-25 /pmc/articles/PMC9712565/ /pubmed/36468091 http://dx.doi.org/10.1016/j.heliyon.2022.e11887 Text en © 2022 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Research Article He, Yuhang Fu, Zhengyi Dai, Shiming Yu, Gang Ma, Zhenhua Wang, Xiaomei Dietary curcumin supplementation enhances intestinal immunity and gill protection in juvenile greater amberjack (Seriola dumerili) |
title | Dietary curcumin supplementation enhances intestinal immunity and gill protection in juvenile greater amberjack (Seriola dumerili) |
title_full | Dietary curcumin supplementation enhances intestinal immunity and gill protection in juvenile greater amberjack (Seriola dumerili) |
title_fullStr | Dietary curcumin supplementation enhances intestinal immunity and gill protection in juvenile greater amberjack (Seriola dumerili) |
title_full_unstemmed | Dietary curcumin supplementation enhances intestinal immunity and gill protection in juvenile greater amberjack (Seriola dumerili) |
title_short | Dietary curcumin supplementation enhances intestinal immunity and gill protection in juvenile greater amberjack (Seriola dumerili) |
title_sort | dietary curcumin supplementation enhances intestinal immunity and gill protection in juvenile greater amberjack (seriola dumerili) |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712565/ https://www.ncbi.nlm.nih.gov/pubmed/36468091 http://dx.doi.org/10.1016/j.heliyon.2022.e11887 |
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