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Dietary curcumin supplementation enhances intestinal immunity and gill protection in juvenile greater amberjack (Seriola dumerili)

A 8-week feeding trial was conducted to determine the effects of dietary supplementation with curcumin on growth, intestinal health, and gills resistance to ammonia stress in juvenile Seriola dumerili. Three isonitrogenous and isolipidic test diets were prepared by supplementing incremental levels o...

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Detalles Bibliográficos
Autores principales: He, Yuhang, Fu, Zhengyi, Dai, Shiming, Yu, Gang, Ma, Zhenhua, Wang, Xiaomei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712565/
https://www.ncbi.nlm.nih.gov/pubmed/36468091
http://dx.doi.org/10.1016/j.heliyon.2022.e11887
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author He, Yuhang
Fu, Zhengyi
Dai, Shiming
Yu, Gang
Ma, Zhenhua
Wang, Xiaomei
author_facet He, Yuhang
Fu, Zhengyi
Dai, Shiming
Yu, Gang
Ma, Zhenhua
Wang, Xiaomei
author_sort He, Yuhang
collection PubMed
description A 8-week feeding trial was conducted to determine the effects of dietary supplementation with curcumin on growth, intestinal health, and gills resistance to ammonia stress in juvenile Seriola dumerili. Three isonitrogenous and isolipidic test diets were prepared by supplementing incremental levels of dietary curcumin at 0% (CUR0%, control), 0.01% (CUR0.01%), 0.02% (CUR0.02%), respectively. Fish were fed with experimental diet. Recovery and protection capacity after ammonia challenge assay was adopted to test the effect of curcumin. At the end of the feeding trial, the results showed that dietary supplementation with proper curcumin level had a significant positive effect on fish survival and intestinal histology structure. Meanwhile, dietary supplementation with proper curcumin level can improve intestinal health by increasing immune enzyme activity, up-regulating the expression of anti-inflammatory cytokines, down-regulating the expression of pro-inflammatory cytokines and regulating other immune-related genes. Subsequently, after the ammonia challenge and recovery experiment, the results of antioxidant-related genes and antioxidant enzymes showed that dietary supplementation with proper curcumin level can improve the gill protective and recovery capacity from ammonia stress through increasing antioxidant capacity. These results suggest that dietary supplementation with proper curcumin can promote the growth, intestinal health, gill resistance and recovery to ammonia stress of S. dumerili.
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spelling pubmed-97125652022-12-02 Dietary curcumin supplementation enhances intestinal immunity and gill protection in juvenile greater amberjack (Seriola dumerili) He, Yuhang Fu, Zhengyi Dai, Shiming Yu, Gang Ma, Zhenhua Wang, Xiaomei Heliyon Research Article A 8-week feeding trial was conducted to determine the effects of dietary supplementation with curcumin on growth, intestinal health, and gills resistance to ammonia stress in juvenile Seriola dumerili. Three isonitrogenous and isolipidic test diets were prepared by supplementing incremental levels of dietary curcumin at 0% (CUR0%, control), 0.01% (CUR0.01%), 0.02% (CUR0.02%), respectively. Fish were fed with experimental diet. Recovery and protection capacity after ammonia challenge assay was adopted to test the effect of curcumin. At the end of the feeding trial, the results showed that dietary supplementation with proper curcumin level had a significant positive effect on fish survival and intestinal histology structure. Meanwhile, dietary supplementation with proper curcumin level can improve intestinal health by increasing immune enzyme activity, up-regulating the expression of anti-inflammatory cytokines, down-regulating the expression of pro-inflammatory cytokines and regulating other immune-related genes. Subsequently, after the ammonia challenge and recovery experiment, the results of antioxidant-related genes and antioxidant enzymes showed that dietary supplementation with proper curcumin level can improve the gill protective and recovery capacity from ammonia stress through increasing antioxidant capacity. These results suggest that dietary supplementation with proper curcumin can promote the growth, intestinal health, gill resistance and recovery to ammonia stress of S. dumerili. Elsevier 2022-11-25 /pmc/articles/PMC9712565/ /pubmed/36468091 http://dx.doi.org/10.1016/j.heliyon.2022.e11887 Text en © 2022 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Research Article
He, Yuhang
Fu, Zhengyi
Dai, Shiming
Yu, Gang
Ma, Zhenhua
Wang, Xiaomei
Dietary curcumin supplementation enhances intestinal immunity and gill protection in juvenile greater amberjack (Seriola dumerili)
title Dietary curcumin supplementation enhances intestinal immunity and gill protection in juvenile greater amberjack (Seriola dumerili)
title_full Dietary curcumin supplementation enhances intestinal immunity and gill protection in juvenile greater amberjack (Seriola dumerili)
title_fullStr Dietary curcumin supplementation enhances intestinal immunity and gill protection in juvenile greater amberjack (Seriola dumerili)
title_full_unstemmed Dietary curcumin supplementation enhances intestinal immunity and gill protection in juvenile greater amberjack (Seriola dumerili)
title_short Dietary curcumin supplementation enhances intestinal immunity and gill protection in juvenile greater amberjack (Seriola dumerili)
title_sort dietary curcumin supplementation enhances intestinal immunity and gill protection in juvenile greater amberjack (seriola dumerili)
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712565/
https://www.ncbi.nlm.nih.gov/pubmed/36468091
http://dx.doi.org/10.1016/j.heliyon.2022.e11887
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