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Mosaic loss of Chromosome Y in aged human microglia
Mosaic loss of Chromosome Y (LOY) is a common acquired structural mutation in the leukocytes of aging men that is correlated with several age-related diseases, including Alzheimer's disease (AD). The molecular basis of LOY in brain cells has not been systematically investigated. Here, we presen...
Autores principales: | Vermeulen, Michael C., Pearse, Richard, Young-Pearse, Tracy, Mostafavi, Sara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712627/ https://www.ncbi.nlm.nih.gov/pubmed/36041859 http://dx.doi.org/10.1101/gr.276409.121 |
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