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Archaic introgression contributed to the pre-agriculture adaptation of vitamin B1 metabolism in East Asia
Thiamine (vitamin B1) is an essential micronutrient. Genes involved in thiamine metabolisms, such as SLC19A2, SLC35F3, and SLC35F4, were assumed to be underlying positive selection in East Asians, but the detailed mechanism remains unknown. Here, we analyzed genome data of 3,823 individuals represen...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712685/ https://www.ncbi.nlm.nih.gov/pubmed/36465121 http://dx.doi.org/10.1016/j.isci.2022.105614 |