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GSK3α phosphorylates dynamin-2 to promote GLUT4 endocytosis in muscle cells
Insulin-stimulated translocation of glucose transporter 4 (GLUT4) to plasma membrane of skeletal muscle is critical for postprandial glucose uptake; however, whether the internalization of GLUT4 is also regulated by insulin signaling remains unclear. Here, we discover that the activity of dynamin-2...
Autores principales: | Laiman, Jessica, Hsu, Yen-Jung, Loh, Julie, Tang, Wei-Chun, Chuang, Mei-Chun, Liu, Hui-Kang, Yang, Wei-Shun, Chen, Bi-Chang, Chuang, Lee-Ming, Chang, Yi-Cheng, Liu, Ya-Wen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712776/ https://www.ncbi.nlm.nih.gov/pubmed/36445308 http://dx.doi.org/10.1083/jcb.202102119 |
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