The filarial and the antibiotics: Single or combination therapy using antibiotics for filariasis

Filarial infections caused by nematodes are one of the major neglected tropical diseases with public health concern. Although there is significant decrease in microfilariae (mf) prevalence following mass drug administration (IVM/DEC/ALB administration), this is transient, in that there is reported m...

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Autores principales: Fordjour, Fatima Amponsah, Kwarteng, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712956/
https://www.ncbi.nlm.nih.gov/pubmed/36467729
http://dx.doi.org/10.3389/fcimb.2022.1044412
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author Fordjour, Fatima Amponsah
Kwarteng, Alexander
author_facet Fordjour, Fatima Amponsah
Kwarteng, Alexander
author_sort Fordjour, Fatima Amponsah
collection PubMed
description Filarial infections caused by nematodes are one of the major neglected tropical diseases with public health concern. Although there is significant decrease in microfilariae (mf) prevalence following mass drug administration (IVM/DEC/ALB administration), this is transient, in that there is reported microfilaria repopulation 6-12 months after treatment. Wolbachia bacteria have been recommended as a novel target presenting antibiotic-based treatment for filarial disease. Potency of antibiotics against filarial diseases is undoubtful, however, the duration for treatment remains a hurdle yet to be overcome in filarial disease treatment.
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spelling pubmed-97129562022-12-02 The filarial and the antibiotics: Single or combination therapy using antibiotics for filariasis Fordjour, Fatima Amponsah Kwarteng, Alexander Front Cell Infect Microbiol Cellular and Infection Microbiology Filarial infections caused by nematodes are one of the major neglected tropical diseases with public health concern. Although there is significant decrease in microfilariae (mf) prevalence following mass drug administration (IVM/DEC/ALB administration), this is transient, in that there is reported microfilaria repopulation 6-12 months after treatment. Wolbachia bacteria have been recommended as a novel target presenting antibiotic-based treatment for filarial disease. Potency of antibiotics against filarial diseases is undoubtful, however, the duration for treatment remains a hurdle yet to be overcome in filarial disease treatment. Frontiers Media S.A. 2022-11-17 /pmc/articles/PMC9712956/ /pubmed/36467729 http://dx.doi.org/10.3389/fcimb.2022.1044412 Text en Copyright © 2022 Fordjour and Kwarteng https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cellular and Infection Microbiology
Fordjour, Fatima Amponsah
Kwarteng, Alexander
The filarial and the antibiotics: Single or combination therapy using antibiotics for filariasis
title The filarial and the antibiotics: Single or combination therapy using antibiotics for filariasis
title_full The filarial and the antibiotics: Single or combination therapy using antibiotics for filariasis
title_fullStr The filarial and the antibiotics: Single or combination therapy using antibiotics for filariasis
title_full_unstemmed The filarial and the antibiotics: Single or combination therapy using antibiotics for filariasis
title_short The filarial and the antibiotics: Single or combination therapy using antibiotics for filariasis
title_sort filarial and the antibiotics: single or combination therapy using antibiotics for filariasis
topic Cellular and Infection Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712956/
https://www.ncbi.nlm.nih.gov/pubmed/36467729
http://dx.doi.org/10.3389/fcimb.2022.1044412
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