A noncanonical RNA-binding domain of the fragile X protein, FMRP, elicits translational repression independent of mRNA G-quadruplexes

Loss of functional fragile X mental retardation protein (FMRP) causes fragile X syndrome, the leading form of inherited intellectual disability and the most common monogenic cause of autism spectrum disorders. FMRP is an RNA-binding protein that controls neuronal mRNA localization and translation. F...

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Detalles Bibliográficos
Autores principales: Scarpitti, MaKenzie R., Warrick, Julia E., Yoder, Evelyn L., Kearse, Michael G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712993/
https://www.ncbi.nlm.nih.gov/pubmed/36328245
http://dx.doi.org/10.1016/j.jbc.2022.102660

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712993/
https://www.ncbi.nlm.nih.gov/pubmed/36328245
http://dx.doi.org/10.1016/j.jbc.2022.102660

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