PML at mitochondria-associated membranes governs a trimeric complex with NLRP3 and P2X7R that modulates the tumor immune microenvironment

Uncontrolled inflammatory response arising from the tumor microenvironment (TME) significantly contributes to cancer progression, prompting an investigation and careful evaluation of counter-regulatory mechanisms. We identified a trimeric complex at the mitochondria-associated membranes (MAMs), in w...

Descripción completa

Detalles Bibliográficos
Autores principales: Missiroli, Sonia, Perrone, Mariasole, Gafà, Roberta, Nicoli, Francesco, Bonora, Massimo, Morciano, Giampaolo, Boncompagni, Caterina, Marchi, Saverio, Lebiedzinska-Arciszewska, Magdalena, Vezzani, Bianca, Lanza, Giovanni, Kricek, Franz, Borghi, Alessandro, Fiorica, Francesco, Ito, Keisuke, Wieckowski, Mariusz R., Di Virgilio, Francesco, Abelli, Luigi, Pinton, Paolo, Giorgi, Carlotta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713080/
https://www.ncbi.nlm.nih.gov/pubmed/36450825
http://dx.doi.org/10.1038/s41418-022-01095-9

Ejemplares similares

Ejemplares similares