Cytokines and cytokine receptors as targets of immune-mediated inflammatory diseases—RA as a role model

Recent advances in our understanding in the immune-mediated inflammatory diseases (IMID) are explored and promoted by the targeted treatment. Among these targets, cytokines and cytokine receptors have become the good candidates for the drug development. In this review, the cytokine and cytokine rece...

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Autor principal: Takeuchi, Tsutomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713106/
https://www.ncbi.nlm.nih.gov/pubmed/36451227
http://dx.doi.org/10.1186/s41232-022-00221-x
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author Takeuchi, Tsutomu
author_facet Takeuchi, Tsutomu
author_sort Takeuchi, Tsutomu
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description Recent advances in our understanding in the immune-mediated inflammatory diseases (IMID) are explored and promoted by the targeted treatment. Among these targets, cytokines and cytokine receptors have become the good candidates for the drug development. In this review, the cytokine and cytokine receptors, which are approved in IMID, are overviewed, and modalities of the treatment, the role of cytokines and cytokine receptors in each disease, and the updated molecular information by modern technologies in rheumatoid arthritis as a role model are shown and discussed for the future perspectives.
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spelling pubmed-97131062022-12-01 Cytokines and cytokine receptors as targets of immune-mediated inflammatory diseases—RA as a role model Takeuchi, Tsutomu Inflamm Regen Review Recent advances in our understanding in the immune-mediated inflammatory diseases (IMID) are explored and promoted by the targeted treatment. Among these targets, cytokines and cytokine receptors have become the good candidates for the drug development. In this review, the cytokine and cytokine receptors, which are approved in IMID, are overviewed, and modalities of the treatment, the role of cytokines and cytokine receptors in each disease, and the updated molecular information by modern technologies in rheumatoid arthritis as a role model are shown and discussed for the future perspectives. BioMed Central 2022-12-01 /pmc/articles/PMC9713106/ /pubmed/36451227 http://dx.doi.org/10.1186/s41232-022-00221-x Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Review
Takeuchi, Tsutomu
Cytokines and cytokine receptors as targets of immune-mediated inflammatory diseases—RA as a role model
title Cytokines and cytokine receptors as targets of immune-mediated inflammatory diseases—RA as a role model
title_full Cytokines and cytokine receptors as targets of immune-mediated inflammatory diseases—RA as a role model
title_fullStr Cytokines and cytokine receptors as targets of immune-mediated inflammatory diseases—RA as a role model
title_full_unstemmed Cytokines and cytokine receptors as targets of immune-mediated inflammatory diseases—RA as a role model
title_short Cytokines and cytokine receptors as targets of immune-mediated inflammatory diseases—RA as a role model
title_sort cytokines and cytokine receptors as targets of immune-mediated inflammatory diseases—ra as a role model
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713106/
https://www.ncbi.nlm.nih.gov/pubmed/36451227
http://dx.doi.org/10.1186/s41232-022-00221-x
work_keys_str_mv AT takeuchitsutomu cytokinesandcytokinereceptorsastargetsofimmunemediatedinflammatorydiseasesraasarolemodel

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