Cargando…

The extracellular matrix controls stem cell specification and crypt morphology in the developing and adult mouse gut

The rapid renewal of the epithelial gut lining is fuelled by stem cells that reside at the base of intestinal crypts. The signal transduction pathways and morphogens that regulate intestinal stem cell self-renewal and differentiation have been extensively characterised. In contrast, although extrace...

Descripción completa

Detalles Bibliográficos
Autores principales: Ramadan, Rana, Wouters, Valérie M., van Neerven, Sanne M., de Groot, Nina E., Garcia, Tania Martins, Muncan, Vanessa, Franklin, Olivia D., Battle, Michelle, Carlson, Karen Sue, Leach, Joshua, Sansom, Owen J., Boulard, Olivier, Chamaillard, Mathias, Vermeulen, Louis, Medema, Jan Paul, Huels, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713296/
https://www.ncbi.nlm.nih.gov/pubmed/36350252
http://dx.doi.org/10.1242/bio.059544