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The extracellular matrix controls stem cell specification and crypt morphology in the developing and adult mouse gut
The rapid renewal of the epithelial gut lining is fuelled by stem cells that reside at the base of intestinal crypts. The signal transduction pathways and morphogens that regulate intestinal stem cell self-renewal and differentiation have been extensively characterised. In contrast, although extrace...
Autores principales: | Ramadan, Rana, Wouters, Valérie M., van Neerven, Sanne M., de Groot, Nina E., Garcia, Tania Martins, Muncan, Vanessa, Franklin, Olivia D., Battle, Michelle, Carlson, Karen Sue, Leach, Joshua, Sansom, Owen J., Boulard, Olivier, Chamaillard, Mathias, Vermeulen, Louis, Medema, Jan Paul, Huels, David J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713296/ https://www.ncbi.nlm.nih.gov/pubmed/36350252 http://dx.doi.org/10.1242/bio.059544 |
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