A Novel B7-H6–Targeted IgG-Like T Cell–Engaging Antibody for the Treatment of Gastrointestinal Tumors

PURPOSE: Advanced-stage gastrointestinal cancers represent a high unmet need requiring new effective therapies. We investigated the antitumor activity of a novel T cell–engaging antibody (B7-H6/CD3 ITE) targeting B7-H6, a tumor-associated antigen that is expressed in gastrointestinal tumors. EXPERIM...

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Detalles Bibliográficos
Autores principales: Zhang, Wei, Auguste, Aurélie, Liao, Xiaoyun, Walterskirchen, Christian, Bauer, Kathrin, Lin, Yu-Hsi, Yang, Ling, Sayedian, Farzaneh, Fabits, Markus, Bergmann, Michael, Binder, Carina, Corrales, Leticia, Vogt, Anne B., Hudson, Lindsey J., Barnes, Martin P., Bisht, Arnima, Giragossian, Craig, Voynov, Vladimir, Adam, Paul J., Hipp, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Translational Cancer Mechanisms and Therapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713360/
https://www.ncbi.nlm.nih.gov/pubmed/36166004
http://dx.doi.org/10.1158/1078-0432.CCR-22-2108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713360/
https://www.ncbi.nlm.nih.gov/pubmed/36166004
http://dx.doi.org/10.1158/1078-0432.CCR-22-2108

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