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Activation of Adaptive and Innate Immune Cells via Localized IL2 Cytokine Factories Eradicates Mesothelioma Tumors

PURPOSE: IL2 immunotherapy has the potential to elicit immune-mediated tumor lysis via activation of effector immune cells, but clinical utility is limited due to pharmacokinetic challenges as well as vascular leak syndrome and other life-threatening toxicities experienced by patients. We developed...

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Detalles Bibliográficos
Autores principales:	Nash, Amanda M., Aghlara-Fotovat, Samira, Castillio, Bertha, Hernandez, Andrea, Pugazenthi, Aarthi, Lee, Hyun-Sung, Jang, Hee-Jin, Nguyen, Annie, Lu, Alexander, Burt, Bryan M., Ghanta, Ravi K., Veiseh, Omid
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for Cancer Research 2022
Materias:	Translational Cancer Mechanisms and Therapy
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713361/ https://www.ncbi.nlm.nih.gov/pubmed/35993913 http://dx.doi.org/10.1158/1078-0432.CCR-22-1493

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