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Genomics of sexual cell fate transdifferentiation in the mouse gonad

Sex determination in mammals hinges on a cell fate decision in the fetal bipotential gonad between formation of male Sertoli cells or female granulosa cells. While this decision normally is permanent, loss of key cell fate regulators such as the transcription factors Dmrt1 and Foxl2 can cause postna...

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Detalles Bibliográficos
Autores principales:	Murphy, Mark W, Gearhart, Micah D, Wheeler, Andrew, Bardwell, Vivian J, Zarkower, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713387/ https://www.ncbi.nlm.nih.gov/pubmed/36200842 http://dx.doi.org/10.1093/g3journal/jkac267

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