Assessing single-locus CRISPR/Cas9-based gene drive variants in the mosquito Aedes aegypti via single-generation crosses and modeling

The yellow fever mosquito Aedes aegypti is a major vector of arthropod-borne viruses, including dengue, chikungunya, and Zika viruses. A novel approach to mitigate arboviral infections is to generate mosquitoes refractory to infection by overexpressing antiviral effector molecules. Such an approach...

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Detalles Bibliográficos
Autores principales: Reid, William, Williams, Adeline E, Sanchez-Vargas, Irma, Lin, Jingyi, Juncu, Rucsanda, Olson, Ken E, Franz, Alexander W E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713460/
https://www.ncbi.nlm.nih.gov/pubmed/36250791
http://dx.doi.org/10.1093/g3journal/jkac280

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