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Comparative single-cell RNA-sequencing profiling of BMP4-treated primary glioma cultures reveals therapeutic markers

BACKGROUND: Glioblastoma (GBM) is the most aggressive primary brain tumor. Its cellular composition is very heterogeneous, with cells exhibiting stem-cell characteristics (GSCs) that co-determine therapy resistance and tumor recurrence. Bone Morphogenetic Protein (BMP)-4 promotes astroglial and supp...

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Detalles Bibliográficos
Autores principales:	Verploegh, Iris S C, Conidi, Andrea, Brouwer, Rutger W W, Balcioglu, Hayri E, Karras, Panagiotis, Makhzami, Samira, Korporaal, Anne, Marine, Jean-Christophe, Lamfers, Martine, Van IJcken, Wilfred F J, Leenstra, Sieger, Huylebroeck, Danny
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Basic and Translational Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713526/ https://www.ncbi.nlm.nih.gov/pubmed/35639831 http://dx.doi.org/10.1093/neuonc/noac143

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