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Uncovering the Impact of Control Strategies on the Transmission Pattern of SARS-CoV-2 — Ruili City, Yunnan Province, China, February–March 2022

INTRODUCTION: The implementation of public health and social measures (PHSMs) was an effective option for controlling coronavirus disease 2019 (COVID-19). However, evidence is needed to evaluate these PHSMs’ effects on the recently emerged variant Omicron. METHODS: This study investigated variant Om...

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Autores principales: Chen, Jinou, Qiu, Yubing, Shi, Yuhua, Wu, Wei, Zheng, Erda, Xu, Lin, Jia, Manhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Office of CCDCW, Chinese Center for Disease Control and Prevention 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713571/
https://www.ncbi.nlm.nih.gov/pubmed/36483190
http://dx.doi.org/10.46234/ccdcw2022.208
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author Chen, Jinou
Qiu, Yubing
Shi, Yuhua
Wu, Wei
Zheng, Erda
Xu, Lin
Jia, Manhong
author_facet Chen, Jinou
Qiu, Yubing
Shi, Yuhua
Wu, Wei
Zheng, Erda
Xu, Lin
Jia, Manhong
author_sort Chen, Jinou
collection PubMed
description INTRODUCTION: The implementation of public health and social measures (PHSMs) was an effective option for controlling coronavirus disease 2019 (COVID-19). However, evidence is needed to evaluate these PHSMs’ effects on the recently emerged variant Omicron. METHODS: This study investigated variant Omicron BA.2’s outbreak in Ruili City, Yunnan Province, China. The disease transmission dynamics, spatiotemporal interactions, and transmission networks were analyzed to illustrate the effect of PHSM strategies on Omicron spread. RESULTS: A total of 387 cases were related to the outbreak. The time-varying reproduction number was synchronized with PHSM strategies. Spatiotemporal clustering strength presented heterogeneity and hotspots. Restricted strategies suppressed temporal and spatial relative risk compared with routine and upgraded strategies. The transmission network presented a steeper degree distribution and a heavier tail under upgraded strategies. Phase transformation and distinctive transmission patterns were observed from strategy-stratified subnetworks. CONCLUSIONS: The tightened response strategy contained reproduction of the virus, suppressed spatiotemporal clustering, and reshaped the networks of COVID-19 Omicron variant transmission. As such, PHSMs against Omicron are likely to benefit future responses as well.
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spelling pubmed-97135712022-12-07 Uncovering the Impact of Control Strategies on the Transmission Pattern of SARS-CoV-2 — Ruili City, Yunnan Province, China, February–March 2022 Chen, Jinou Qiu, Yubing Shi, Yuhua Wu, Wei Zheng, Erda Xu, Lin Jia, Manhong China CDC Wkly Methods and Applications INTRODUCTION: The implementation of public health and social measures (PHSMs) was an effective option for controlling coronavirus disease 2019 (COVID-19). However, evidence is needed to evaluate these PHSMs’ effects on the recently emerged variant Omicron. METHODS: This study investigated variant Omicron BA.2’s outbreak in Ruili City, Yunnan Province, China. The disease transmission dynamics, spatiotemporal interactions, and transmission networks were analyzed to illustrate the effect of PHSM strategies on Omicron spread. RESULTS: A total of 387 cases were related to the outbreak. The time-varying reproduction number was synchronized with PHSM strategies. Spatiotemporal clustering strength presented heterogeneity and hotspots. Restricted strategies suppressed temporal and spatial relative risk compared with routine and upgraded strategies. The transmission network presented a steeper degree distribution and a heavier tail under upgraded strategies. Phase transformation and distinctive transmission patterns were observed from strategy-stratified subnetworks. CONCLUSIONS: The tightened response strategy contained reproduction of the virus, suppressed spatiotemporal clustering, and reshaped the networks of COVID-19 Omicron variant transmission. As such, PHSMs against Omicron are likely to benefit future responses as well. Editorial Office of CCDCW, Chinese Center for Disease Control and Prevention 2022-11-18 /pmc/articles/PMC9713571/ /pubmed/36483190 http://dx.doi.org/10.46234/ccdcw2022.208 Text en Copyright and License information: Editorial Office of CCDCW, Chinese Center for Disease Control and Prevention 2022 https://creativecommons.org/licenses/by-nc-sa/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial-Share Alike 4.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/4.0/ (https://creativecommons.org/licenses/by-nc-sa/4.0/)
spellingShingle Methods and Applications
Chen, Jinou
Qiu, Yubing
Shi, Yuhua
Wu, Wei
Zheng, Erda
Xu, Lin
Jia, Manhong
Uncovering the Impact of Control Strategies on the Transmission Pattern of SARS-CoV-2 — Ruili City, Yunnan Province, China, February–March 2022
title Uncovering the Impact of Control Strategies on the Transmission Pattern of SARS-CoV-2 — Ruili City, Yunnan Province, China, February–March 2022
title_full Uncovering the Impact of Control Strategies on the Transmission Pattern of SARS-CoV-2 — Ruili City, Yunnan Province, China, February–March 2022
title_fullStr Uncovering the Impact of Control Strategies on the Transmission Pattern of SARS-CoV-2 — Ruili City, Yunnan Province, China, February–March 2022
title_full_unstemmed Uncovering the Impact of Control Strategies on the Transmission Pattern of SARS-CoV-2 — Ruili City, Yunnan Province, China, February–March 2022
title_short Uncovering the Impact of Control Strategies on the Transmission Pattern of SARS-CoV-2 — Ruili City, Yunnan Province, China, February–March 2022
title_sort uncovering the impact of control strategies on the transmission pattern of sars-cov-2 — ruili city, yunnan province, china, february–march 2022
topic Methods and Applications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713571/
https://www.ncbi.nlm.nih.gov/pubmed/36483190
http://dx.doi.org/10.46234/ccdcw2022.208
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