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Uncovering the Impact of Control Strategies on the Transmission Pattern of SARS-CoV-2 — Ruili City, Yunnan Province, China, February–March 2022
INTRODUCTION: The implementation of public health and social measures (PHSMs) was an effective option for controlling coronavirus disease 2019 (COVID-19). However, evidence is needed to evaluate these PHSMs’ effects on the recently emerged variant Omicron. METHODS: This study investigated variant Om...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Editorial Office of CCDCW, Chinese Center for Disease Control and Prevention
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713571/ https://www.ncbi.nlm.nih.gov/pubmed/36483190 http://dx.doi.org/10.46234/ccdcw2022.208 |
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author | Chen, Jinou Qiu, Yubing Shi, Yuhua Wu, Wei Zheng, Erda Xu, Lin Jia, Manhong |
author_facet | Chen, Jinou Qiu, Yubing Shi, Yuhua Wu, Wei Zheng, Erda Xu, Lin Jia, Manhong |
author_sort | Chen, Jinou |
collection | PubMed |
description | INTRODUCTION: The implementation of public health and social measures (PHSMs) was an effective option for controlling coronavirus disease 2019 (COVID-19). However, evidence is needed to evaluate these PHSMs’ effects on the recently emerged variant Omicron. METHODS: This study investigated variant Omicron BA.2’s outbreak in Ruili City, Yunnan Province, China. The disease transmission dynamics, spatiotemporal interactions, and transmission networks were analyzed to illustrate the effect of PHSM strategies on Omicron spread. RESULTS: A total of 387 cases were related to the outbreak. The time-varying reproduction number was synchronized with PHSM strategies. Spatiotemporal clustering strength presented heterogeneity and hotspots. Restricted strategies suppressed temporal and spatial relative risk compared with routine and upgraded strategies. The transmission network presented a steeper degree distribution and a heavier tail under upgraded strategies. Phase transformation and distinctive transmission patterns were observed from strategy-stratified subnetworks. CONCLUSIONS: The tightened response strategy contained reproduction of the virus, suppressed spatiotemporal clustering, and reshaped the networks of COVID-19 Omicron variant transmission. As such, PHSMs against Omicron are likely to benefit future responses as well. |
format | Online Article Text |
id | pubmed-9713571 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Editorial Office of CCDCW, Chinese Center for Disease Control and Prevention |
record_format | MEDLINE/PubMed |
spelling | pubmed-97135712022-12-07 Uncovering the Impact of Control Strategies on the Transmission Pattern of SARS-CoV-2 — Ruili City, Yunnan Province, China, February–March 2022 Chen, Jinou Qiu, Yubing Shi, Yuhua Wu, Wei Zheng, Erda Xu, Lin Jia, Manhong China CDC Wkly Methods and Applications INTRODUCTION: The implementation of public health and social measures (PHSMs) was an effective option for controlling coronavirus disease 2019 (COVID-19). However, evidence is needed to evaluate these PHSMs’ effects on the recently emerged variant Omicron. METHODS: This study investigated variant Omicron BA.2’s outbreak in Ruili City, Yunnan Province, China. The disease transmission dynamics, spatiotemporal interactions, and transmission networks were analyzed to illustrate the effect of PHSM strategies on Omicron spread. RESULTS: A total of 387 cases were related to the outbreak. The time-varying reproduction number was synchronized with PHSM strategies. Spatiotemporal clustering strength presented heterogeneity and hotspots. Restricted strategies suppressed temporal and spatial relative risk compared with routine and upgraded strategies. The transmission network presented a steeper degree distribution and a heavier tail under upgraded strategies. Phase transformation and distinctive transmission patterns were observed from strategy-stratified subnetworks. CONCLUSIONS: The tightened response strategy contained reproduction of the virus, suppressed spatiotemporal clustering, and reshaped the networks of COVID-19 Omicron variant transmission. As such, PHSMs against Omicron are likely to benefit future responses as well. Editorial Office of CCDCW, Chinese Center for Disease Control and Prevention 2022-11-18 /pmc/articles/PMC9713571/ /pubmed/36483190 http://dx.doi.org/10.46234/ccdcw2022.208 Text en Copyright and License information: Editorial Office of CCDCW, Chinese Center for Disease Control and Prevention 2022 https://creativecommons.org/licenses/by-nc-sa/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial-Share Alike 4.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/4.0/ (https://creativecommons.org/licenses/by-nc-sa/4.0/) |
spellingShingle | Methods and Applications Chen, Jinou Qiu, Yubing Shi, Yuhua Wu, Wei Zheng, Erda Xu, Lin Jia, Manhong Uncovering the Impact of Control Strategies on the Transmission Pattern of SARS-CoV-2 — Ruili City, Yunnan Province, China, February–March 2022 |
title | Uncovering the Impact of Control Strategies on the Transmission Pattern of SARS-CoV-2 — Ruili City, Yunnan Province, China, February–March 2022 |
title_full | Uncovering the Impact of Control Strategies on the Transmission Pattern of SARS-CoV-2 — Ruili City, Yunnan Province, China, February–March 2022 |
title_fullStr | Uncovering the Impact of Control Strategies on the Transmission Pattern of SARS-CoV-2 — Ruili City, Yunnan Province, China, February–March 2022 |
title_full_unstemmed | Uncovering the Impact of Control Strategies on the Transmission Pattern of SARS-CoV-2 — Ruili City, Yunnan Province, China, February–March 2022 |
title_short | Uncovering the Impact of Control Strategies on the Transmission Pattern of SARS-CoV-2 — Ruili City, Yunnan Province, China, February–March 2022 |
title_sort | uncovering the impact of control strategies on the transmission pattern of sars-cov-2 — ruili city, yunnan province, china, february–march 2022 |
topic | Methods and Applications |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713571/ https://www.ncbi.nlm.nih.gov/pubmed/36483190 http://dx.doi.org/10.46234/ccdcw2022.208 |
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