In silico and in vitro arboviral MHC class I-restricted-epitope signatures reveal immunodominance and poor overlapping patterns

INTRODUCTION: The present work sought to identify MHC-I-restricted peptide signatures for arbovirus using in silico and in vitro peptide microarray tools. METHODS: First, an in-silico analysis of immunogenic epitopes restricted to four of the most prevalent human MHC class-I was performed by identif...

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Detalles Bibliográficos
Autores principales: Lopes-Ribeiro, Ágata, Araujo, Franklin Pereira, Oliveira, Patrícia de Melo, Teixeira, Lorena de Almeida, Ferreira, Geovane Marques, Lourenço, Alice Aparecida, Dias, Laura Cardoso Corrêa, Teixeira, Caio Wilker, Retes, Henrique Morais, Lopes, Élisson Nogueira, Versiani, Alice Freitas, Barbosa-Stancioli, Edel Figueiredo, da Fonseca, Flávio Guimarães, Martins-Filho, Olindo Assis, Tsuji, Moriya, Peruhype-Magalhães, Vanessa, Coelho-dos-Reis, Jordana Grazziela Alves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713826/
https://www.ncbi.nlm.nih.gov/pubmed/36466864
http://dx.doi.org/10.3389/fimmu.2022.1035515

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