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Activating transcription factor 4 regulates hypoxia inducible factor 1α in chronic hypoxia in pancreatic cancer cells

Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive and difficult to treat cancers with tumors typically exhibiting high levels of chronic hypoxia. Hypoxia activates hypoxia-inducible factors (HIFs) that mediate cellular responses to adapt to low oxygen environments. Hypoxia also c...

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Detalles Bibliográficos
Autores principales:	Chee, Nancy T., Carriere, Candace H., Miller, Zachary, Welford, Scott, Brothers, Shaun P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713860/ https://www.ncbi.nlm.nih.gov/pubmed/36416348 http://dx.doi.org/10.3892/or.2022.8451

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