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Non-Invasive Measurement of the Internal Pressure of a Pressurized Biological Compartment Using Lamb Waves
In this study, we propose a mechanical analysis for estimating the internal pressure of a finitely deformed spherical compartment from Lamb wave measurements. The proposed analysis produces a dispersion relation associating Lamb wave speed with pressure using limited material parameters (only a stra...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713951/ https://www.ncbi.nlm.nih.gov/pubmed/34807817 http://dx.doi.org/10.1109/TBME.2021.3129652 |
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author | Rosen, David P. Larson, Nicholas B. Alizad, Azra Fatemi, Mostafa |
author_facet | Rosen, David P. Larson, Nicholas B. Alizad, Azra Fatemi, Mostafa |
author_sort | Rosen, David P. |
collection | PubMed |
description | In this study, we propose a mechanical analysis for estimating the internal pressure of a finitely deformed spherical compartment from Lamb wave measurements. The proposed analysis produces a dispersion relation associating Lamb wave speed with pressure using limited material parameters (only a strain stiffening term). The analysis was validated on ultrasound bladder vibrometry (UBV) experiments collected from 9 ex vivo porcine bladders before and after formalin cross-linking. Estimated pressures were compared with pressures measured directly by a pressure transducer. The proposed analysis proved broadly effective at estimating pressure from UBV based Lamb wave without calibration as demonstrated by the observed concordance between estimated and measured pressures (Lin’s CCC = 0.82 (0.66–0.91). Theoretical limitations and potential refinements to improve the accuracy and generality of the approach are discussed. |
format | Online Article Text |
id | pubmed-9713951 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
record_format | MEDLINE/PubMed |
spelling | pubmed-97139512022-12-01 Non-Invasive Measurement of the Internal Pressure of a Pressurized Biological Compartment Using Lamb Waves Rosen, David P. Larson, Nicholas B. Alizad, Azra Fatemi, Mostafa IEEE Trans Biomed Eng Article In this study, we propose a mechanical analysis for estimating the internal pressure of a finitely deformed spherical compartment from Lamb wave measurements. The proposed analysis produces a dispersion relation associating Lamb wave speed with pressure using limited material parameters (only a strain stiffening term). The analysis was validated on ultrasound bladder vibrometry (UBV) experiments collected from 9 ex vivo porcine bladders before and after formalin cross-linking. Estimated pressures were compared with pressures measured directly by a pressure transducer. The proposed analysis proved broadly effective at estimating pressure from UBV based Lamb wave without calibration as demonstrated by the observed concordance between estimated and measured pressures (Lin’s CCC = 0.82 (0.66–0.91). Theoretical limitations and potential refinements to improve the accuracy and generality of the approach are discussed. 2022-06 2022-05-19 /pmc/articles/PMC9713951/ /pubmed/34807817 http://dx.doi.org/10.1109/TBME.2021.3129652 Text en https://creativecommons.org/licenses/by/4.0/This work is licensed under a Creative Commons Attribution 4.0 License. For more information, see https://creativecommons.org/licenses/by/4.0/ |
spellingShingle | Article Rosen, David P. Larson, Nicholas B. Alizad, Azra Fatemi, Mostafa Non-Invasive Measurement of the Internal Pressure of a Pressurized Biological Compartment Using Lamb Waves |
title | Non-Invasive Measurement of the Internal Pressure of a Pressurized Biological Compartment Using Lamb Waves |
title_full | Non-Invasive Measurement of the Internal Pressure of a Pressurized Biological Compartment Using Lamb Waves |
title_fullStr | Non-Invasive Measurement of the Internal Pressure of a Pressurized Biological Compartment Using Lamb Waves |
title_full_unstemmed | Non-Invasive Measurement of the Internal Pressure of a Pressurized Biological Compartment Using Lamb Waves |
title_short | Non-Invasive Measurement of the Internal Pressure of a Pressurized Biological Compartment Using Lamb Waves |
title_sort | non-invasive measurement of the internal pressure of a pressurized biological compartment using lamb waves |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713951/ https://www.ncbi.nlm.nih.gov/pubmed/34807817 http://dx.doi.org/10.1109/TBME.2021.3129652 |
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