Determining the effective dose of esketamine for mitigating pain during propofol injection by Dixon’s up-and-down method: a double-blind, prospective clinical study of drug dose response

BACKGROUND: Propofol is an intravenous (IV) anesthetic medication widely used for procedural sedation, operative anesthesia, and in intensive care unit (ICU), but the incidence of pain during IV infusion can reach 28–90%. Ketamine can attenuate pain associated with IV propofol injection through loca...

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Detalles Bibliográficos
Autores principales: Tan, Meiyun, Zhang, Chunyuan, Zeng, Wei, Chen, Maofang, Huang, Zehui, Huang, Ding
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9714076/
https://www.ncbi.nlm.nih.gov/pubmed/36457068
http://dx.doi.org/10.1186/s12871-022-01914-z

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