Proteomic signatures of schizophrenia-sourced iPSC-derived neural cells and brain organoids are similar to patients' postmortem brains

BACKGROUND: Schizophrenia is a complex and severe neuropsychiatric disorder, with a wide range of debilitating symptoms. Several aspects of its multifactorial complexity are still unknown, and some are accepted to be an early developmental deficiency with a more specifically neurodevelopmental origi...

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Detalles Bibliográficos
Autores principales: Nascimento, Juliana Minardi, Saia-Cereda, Verônica M., Zuccoli, Giuliana S., Reis-de-Oliveira, Guilherme, Carregari, Victor Corasolla, Smith, Bradley J., Rehen, Stevens K., Martins-de-Souza, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9714120/
https://www.ncbi.nlm.nih.gov/pubmed/36451159
http://dx.doi.org/10.1186/s13578-022-00928-x

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