Low dimensional nanomaterials for treating acute kidney injury

Acute kidney injury (AKI) is one of the most common severe complications among hospitalized patients. In the absence of specific drugs to treat AKI, hemodialysis remains the primary clinical treatment for AKI patients. AKI treatment has received significant attention recently due to the excellent dr...

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Autores principales: Nie, Yuanpeng, Wang, Liying, You, Xinru, Wang, Xiaohua, Wu, Jun, Zheng, Zhihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9714216/
https://www.ncbi.nlm.nih.gov/pubmed/36456976
http://dx.doi.org/10.1186/s12951-022-01712-2
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author Nie, Yuanpeng
Wang, Liying
You, Xinru
Wang, Xiaohua
Wu, Jun
Zheng, Zhihua
author_facet Nie, Yuanpeng
Wang, Liying
You, Xinru
Wang, Xiaohua
Wu, Jun
Zheng, Zhihua
author_sort Nie, Yuanpeng
collection PubMed
description Acute kidney injury (AKI) is one of the most common severe complications among hospitalized patients. In the absence of specific drugs to treat AKI, hemodialysis remains the primary clinical treatment for AKI patients. AKI treatment has received significant attention recently due to the excellent drug delivery capabilities of low-dimensional nanomaterials (LDNs) and their unique therapeutic effects. Diverse LDNs have been proposed to treat AKI, with promising results and the potential for future clinical application. This article aims to provide an overview of the pathogenesis of AKI and the recent advances in the treatment of AKI using different types of LDNs. In addition, it is intended to provide theoretical support for the design of LDNs and implications for AKI treatment. GRAPHICAL ABSTRACT: [Image: see text]
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spelling pubmed-97142162022-12-02 Low dimensional nanomaterials for treating acute kidney injury Nie, Yuanpeng Wang, Liying You, Xinru Wang, Xiaohua Wu, Jun Zheng, Zhihua J Nanobiotechnology Review Acute kidney injury (AKI) is one of the most common severe complications among hospitalized patients. In the absence of specific drugs to treat AKI, hemodialysis remains the primary clinical treatment for AKI patients. AKI treatment has received significant attention recently due to the excellent drug delivery capabilities of low-dimensional nanomaterials (LDNs) and their unique therapeutic effects. Diverse LDNs have been proposed to treat AKI, with promising results and the potential for future clinical application. This article aims to provide an overview of the pathogenesis of AKI and the recent advances in the treatment of AKI using different types of LDNs. In addition, it is intended to provide theoretical support for the design of LDNs and implications for AKI treatment. GRAPHICAL ABSTRACT: [Image: see text] BioMed Central 2022-12-01 /pmc/articles/PMC9714216/ /pubmed/36456976 http://dx.doi.org/10.1186/s12951-022-01712-2 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Nie, Yuanpeng
Wang, Liying
You, Xinru
Wang, Xiaohua
Wu, Jun
Zheng, Zhihua
Low dimensional nanomaterials for treating acute kidney injury
title Low dimensional nanomaterials for treating acute kidney injury
title_full Low dimensional nanomaterials for treating acute kidney injury
title_fullStr Low dimensional nanomaterials for treating acute kidney injury
title_full_unstemmed Low dimensional nanomaterials for treating acute kidney injury
title_short Low dimensional nanomaterials for treating acute kidney injury
title_sort low dimensional nanomaterials for treating acute kidney injury
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9714216/
https://www.ncbi.nlm.nih.gov/pubmed/36456976
http://dx.doi.org/10.1186/s12951-022-01712-2
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AT wangxiaohua lowdimensionalnanomaterialsfortreatingacutekidneyinjury
AT wujun lowdimensionalnanomaterialsfortreatingacutekidneyinjury
AT zhengzhihua lowdimensionalnanomaterialsfortreatingacutekidneyinjury

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