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Triple network activation causes tinnitus in patients with sudden sensorineural hearing loss: A model-based volume-entropy analysis
Tinnitus can be defined as the conscious perception of phantom sounds in the absence of corresponding external auditory signals. Tinnitus can develop in the setting of sudden sensorineural hearing loss (SSNHL), but the underlying mechanism is largely unknown. Using electroencephalography, we investi...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9714300/ https://www.ncbi.nlm.nih.gov/pubmed/36466160 http://dx.doi.org/10.3389/fnins.2022.1028776 |
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author | Lee, Seung Jae Park, Jaemin Lee, Sang-Yeon Koo, Ja-Won Vanneste, Sven De Ridder, Dirk Lim, Seonhee Song, Jae-Jin |
author_facet | Lee, Seung Jae Park, Jaemin Lee, Sang-Yeon Koo, Ja-Won Vanneste, Sven De Ridder, Dirk Lim, Seonhee Song, Jae-Jin |
author_sort | Lee, Seung Jae |
collection | PubMed |
description | Tinnitus can be defined as the conscious perception of phantom sounds in the absence of corresponding external auditory signals. Tinnitus can develop in the setting of sudden sensorineural hearing loss (SSNHL), but the underlying mechanism is largely unknown. Using electroencephalography, we investigated differences in afferent node capacity between 15 SSNHL patients without tinnitus (NT) and 30 SSNHL patients with tinnitus (T). Where the T group showed increased afferent node capacity in regions constituting a “triple brain network” [default mode network (DMN), central executive network (CEN), and salience network (SN)], the NT group showed increased information flow in regions implicated in temporal auditory processing and noise-canceling pathways. Our results demonstrate that when all components of the triple network are activated due to sudden-onset auditory deprivation, tinnitus ensues. By contrast, auditory processing-associated and tinnitus-suppressing networks are highly activated in the NT group, to overcome the activation of the triple network and effectively suppress the generation of tinnitus. |
format | Online Article Text |
id | pubmed-9714300 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-97143002022-12-02 Triple network activation causes tinnitus in patients with sudden sensorineural hearing loss: A model-based volume-entropy analysis Lee, Seung Jae Park, Jaemin Lee, Sang-Yeon Koo, Ja-Won Vanneste, Sven De Ridder, Dirk Lim, Seonhee Song, Jae-Jin Front Neurosci Neuroscience Tinnitus can be defined as the conscious perception of phantom sounds in the absence of corresponding external auditory signals. Tinnitus can develop in the setting of sudden sensorineural hearing loss (SSNHL), but the underlying mechanism is largely unknown. Using electroencephalography, we investigated differences in afferent node capacity between 15 SSNHL patients without tinnitus (NT) and 30 SSNHL patients with tinnitus (T). Where the T group showed increased afferent node capacity in regions constituting a “triple brain network” [default mode network (DMN), central executive network (CEN), and salience network (SN)], the NT group showed increased information flow in regions implicated in temporal auditory processing and noise-canceling pathways. Our results demonstrate that when all components of the triple network are activated due to sudden-onset auditory deprivation, tinnitus ensues. By contrast, auditory processing-associated and tinnitus-suppressing networks are highly activated in the NT group, to overcome the activation of the triple network and effectively suppress the generation of tinnitus. Frontiers Media S.A. 2022-11-17 /pmc/articles/PMC9714300/ /pubmed/36466160 http://dx.doi.org/10.3389/fnins.2022.1028776 Text en Copyright © 2022 Lee, Park, Lee, Koo, Vanneste, De Ridder, Lim and Song. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Neuroscience Lee, Seung Jae Park, Jaemin Lee, Sang-Yeon Koo, Ja-Won Vanneste, Sven De Ridder, Dirk Lim, Seonhee Song, Jae-Jin Triple network activation causes tinnitus in patients with sudden sensorineural hearing loss: A model-based volume-entropy analysis |
title | Triple network activation causes tinnitus in patients with sudden sensorineural hearing loss: A model-based volume-entropy analysis |
title_full | Triple network activation causes tinnitus in patients with sudden sensorineural hearing loss: A model-based volume-entropy analysis |
title_fullStr | Triple network activation causes tinnitus in patients with sudden sensorineural hearing loss: A model-based volume-entropy analysis |
title_full_unstemmed | Triple network activation causes tinnitus in patients with sudden sensorineural hearing loss: A model-based volume-entropy analysis |
title_short | Triple network activation causes tinnitus in patients with sudden sensorineural hearing loss: A model-based volume-entropy analysis |
title_sort | triple network activation causes tinnitus in patients with sudden sensorineural hearing loss: a model-based volume-entropy analysis |
topic | Neuroscience |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9714300/ https://www.ncbi.nlm.nih.gov/pubmed/36466160 http://dx.doi.org/10.3389/fnins.2022.1028776 |
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