An adaptive phase II/III safety and efficacy randomized controlled trial of single day or three-day fixed-dose albendazole-ivermectin co-formulation versus albendazole for the treatment of Trichuris trichiura and other STH infections. ALIVE trial protocol

Background: Soil-transmitted helminths (STH) are targeted for control through mass drug-administration campaigns to prevent morbidity affecting at-risk groups in endemic regions. Although broadly successful, the use of albendazole and mebendazole achieved variable progress, with deficiencies against...

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Detalles Bibliográficos
Autores principales: Krolewiecki, Alejandro, Enbiale, Wendemagegn, Gandasegui, Javier, van Lieshout, Lisette, Kepha, Stella, Messa Junior, Augusto, Bengtson, Michel, Gelaye, Woyneshet, Escola, Valdemiro, Martinez-Valladares, María, Cambra-Pellejà, María, Algorta, Jaime, Martí-Soler, Helena, Fleitas, Pedro, Ballester, Maria Rosa, Doyle, Stephen R., Williams, Nana Aba, Legarda, Almudena, Mandomando, Inácio, Mwandawiro, Charles, Muñoz, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2022
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9714317/
https://www.ncbi.nlm.nih.gov/pubmed/36540062
http://dx.doi.org/10.12688/gatesopenres.13615.1

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