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Declined adipogenic potential of senescent MSCs due to shift in insulin signaling and altered exosome cargo

Multipotent mesenchymal stromal cells (MSCs) maintain cellular homeostasis and regulate tissue renewal and repair both by differentiating into mesodermal lineage, e.g., adipocytes, or managing the functions of differentiated cells. Insulin is a key physiological inducer of MSC differentiation into a...

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Detalles Bibliográficos
Autores principales:	Voynova, Elizaveta, Kulebyakin, Konstantin, Grigorieva, Olga, Novoseletskaya, Ekaterina, Basalova, Natalia, Alexandrushkina, Natalia, Arbatskiy, Mikhail, Vigovskiy, Maxim, Sorokina, Anna, Zinoveva, Anna, Bakhchinyan, Elizaveta, Kalinina, Natalia, Akopyan, Zhanna, Tkachuk, Vsevolod, Tyurin-Kuzmin, Pyotr, Efimenko, Anastasia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9714334/ https://www.ncbi.nlm.nih.gov/pubmed/36467400 http://dx.doi.org/10.3389/fcell.2022.1050489

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