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Structures of distantly related interacting protein homologs are less divergent than non‐interacting homologs

Homologous proteins can display high structural variation due to evolutionary divergence at low sequence identity. This classical inverse relationship between sequence identity and structural similarity, established many years ago, has remained true between homologous proteins of known structure ove...

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Detalles Bibliográficos
Autores principales: Naveenkumar, Nagarajan, Prabantu, Vasam Manjveekar, Vishwanath, Sneha, Sowdhamini, Ramanathan, Srinivasan, Narayanaswamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9714365/
https://www.ncbi.nlm.nih.gov/pubmed/36148593
http://dx.doi.org/10.1002/2211-5463.13492