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Infección natural por SARS-CoV-2 en gatos y perros domésticos de personas con diagnóstico de COVID-19 en el Valle de Aburrá, Antioquia
INTRODUCTION: The severe acute respiratory syndrome caused by the new coronavirus SARS-CoV-2 is the cause of the health emergency due to the COVID-19 pandemic. Although humans are the main susceptible host, experimental studies and reported cases of natural infection have evidenced scenarios of SARS...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Instituto Nacional de Salud
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9714522/ https://www.ncbi.nlm.nih.gov/pubmed/36322547 http://dx.doi.org/10.7705/biomedica.6407 |
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author | Cabrera, Azucena González-Álvarez, Dubán Gutiérrez, Luz A. Díaz, Francisco J Forero, Diego Rodas, Juan David |
author_facet | Cabrera, Azucena González-Álvarez, Dubán Gutiérrez, Luz A. Díaz, Francisco J Forero, Diego Rodas, Juan David |
author_sort | Cabrera, Azucena |
collection | PubMed |
description | INTRODUCTION: The severe acute respiratory syndrome caused by the new coronavirus SARS-CoV-2 is the cause of the health emergency due to the COVID-19 pandemic. Although humans are the main susceptible host, experimental studies and reported cases of natural infection have evidenced scenarios of SARS-CoV-2 reverse zoonosis in animals. OBJECTIVE: To evaluate the natural infection of SARS-CoV-2 in cats and dogs with owners diagnosed with COVID-19 in the Valle de Aburrá subregion in Antioquia, Colombia. MATERIALS AND METHODS. The circulation of SARS-CoV-2 was evaluated by RT-qPCR and RT-PCR in samples of nasopharyngeal and oropharyngeal smears from cats and dogs whose owners presented latent COVID-19 infection. Positive cases were verified through amplification of N, E and RdRp gene fragments; with the latter being sequenced and the phylogenetically analyzed RESULTS. From 80 tested animals, 6 cats and 3 dogs resulted positive for natural SARS-CoV-2 infection. These animals did not show any clinical signs; and their infected owners only reported mild signs of COVID-19, without clinical complications. Regarding analysis of one of the sequences, a single nucleotide polymorphism (SNP) was found, with a substitution in position 647, resulting in the change of the amino acid serine (S) for isoleucine (I). The cases occurred in the municipalities of Caldas, Medellín and Envigado. CONCLUSIONS. It is inferred that natural infection in cats and dogs is associated with direct contact with a positive COVID-19 patient. |
format | Online Article Text |
id | pubmed-9714522 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Instituto Nacional de Salud |
record_format | MEDLINE/PubMed |
spelling | pubmed-97145222022-12-02 Infección natural por SARS-CoV-2 en gatos y perros domésticos de personas con diagnóstico de COVID-19 en el Valle de Aburrá, Antioquia Cabrera, Azucena González-Álvarez, Dubán Gutiérrez, Luz A. Díaz, Francisco J Forero, Diego Rodas, Juan David Biomedica Artículo Original INTRODUCTION: The severe acute respiratory syndrome caused by the new coronavirus SARS-CoV-2 is the cause of the health emergency due to the COVID-19 pandemic. Although humans are the main susceptible host, experimental studies and reported cases of natural infection have evidenced scenarios of SARS-CoV-2 reverse zoonosis in animals. OBJECTIVE: To evaluate the natural infection of SARS-CoV-2 in cats and dogs with owners diagnosed with COVID-19 in the Valle de Aburrá subregion in Antioquia, Colombia. MATERIALS AND METHODS. The circulation of SARS-CoV-2 was evaluated by RT-qPCR and RT-PCR in samples of nasopharyngeal and oropharyngeal smears from cats and dogs whose owners presented latent COVID-19 infection. Positive cases were verified through amplification of N, E and RdRp gene fragments; with the latter being sequenced and the phylogenetically analyzed RESULTS. From 80 tested animals, 6 cats and 3 dogs resulted positive for natural SARS-CoV-2 infection. These animals did not show any clinical signs; and their infected owners only reported mild signs of COVID-19, without clinical complications. Regarding analysis of one of the sequences, a single nucleotide polymorphism (SNP) was found, with a substitution in position 647, resulting in the change of the amino acid serine (S) for isoleucine (I). The cases occurred in the municipalities of Caldas, Medellín and Envigado. CONCLUSIONS. It is inferred that natural infection in cats and dogs is associated with direct contact with a positive COVID-19 patient. Instituto Nacional de Salud 2022-10-31 /pmc/articles/PMC9714522/ /pubmed/36322547 http://dx.doi.org/10.7705/biomedica.6407 Text en https://creativecommons.org/licenses/by/4.0/Este es un artículo publicado en acceso abierto bajo una licencia Creative Commons |
spellingShingle | Artículo Original Cabrera, Azucena González-Álvarez, Dubán Gutiérrez, Luz A. Díaz, Francisco J Forero, Diego Rodas, Juan David Infección natural por SARS-CoV-2 en gatos y perros domésticos de personas con diagnóstico de COVID-19 en el Valle de Aburrá, Antioquia |
title | Infección natural por SARS-CoV-2 en gatos y perros domésticos de personas con diagnóstico de COVID-19 en el Valle de Aburrá, Antioquia |
title_full | Infección natural por SARS-CoV-2 en gatos y perros domésticos de personas con diagnóstico de COVID-19 en el Valle de Aburrá, Antioquia |
title_fullStr | Infección natural por SARS-CoV-2 en gatos y perros domésticos de personas con diagnóstico de COVID-19 en el Valle de Aburrá, Antioquia |
title_full_unstemmed | Infección natural por SARS-CoV-2 en gatos y perros domésticos de personas con diagnóstico de COVID-19 en el Valle de Aburrá, Antioquia |
title_short | Infección natural por SARS-CoV-2 en gatos y perros domésticos de personas con diagnóstico de COVID-19 en el Valle de Aburrá, Antioquia |
title_sort | infección natural por sars-cov-2 en gatos y perros domésticos de personas con diagnóstico de covid-19 en el valle de aburrá, antioquia |
topic | Artículo Original |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9714522/ https://www.ncbi.nlm.nih.gov/pubmed/36322547 http://dx.doi.org/10.7705/biomedica.6407 |
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