Age related immune modulation of experimental autoimmune encephalomyelitis in PINK1 knockout mice

OBJECTIVE: Recent research has shown that Parkin, an E3 ubiquitin ligase, modulates peripheral immune cells-mediated immunity during experimental autoimmune encephalomyelitis (EAE). Because the PTEN-induced putative kinase 1 (PINK1) protein acts upstream of Parkin in a common mitochondrial quality c...

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Detalles Bibliográficos
Autores principales: Cossu, Davide, Yokoyama, Kazumasa, Sato, Shigeto, Noda, Sachiko, Sakanishi, Tamami, Sechi, Leonardo Antonio, Hattori, Nobutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9714542/
https://www.ncbi.nlm.nih.gov/pubmed/36466826
http://dx.doi.org/10.3389/fimmu.2022.1036680

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9714542/
https://www.ncbi.nlm.nih.gov/pubmed/36466826
http://dx.doi.org/10.3389/fimmu.2022.1036680

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