ECPPF (E2F1, CCNA2, POLE, PPP2R1A, FBXW7) stratification: Profiling high-risk subtypes of histomorphologically low-risk and treatment-insensitive endometrioid endometrial cancer

In endometrial cancer, occult high-risk subtypes (rooted in histomorphologically low-risk disease) with insensitivity to adjuvant therapies impede improvements in therapeutic efficacy. Therefore, we aimed to assess the ability of molecular high-risk (MHR) and low-risk (MLR) ECPPF (E2F1, CCNA2, POLE,...

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Detalles Bibliográficos
Autores principales: Gonzalez-Bosquet, Jesus, Weroha, S. John, Bakkum-Gamez, Jamie N., Weaver, Amy L., McGree, Michaela E., Dowdy, Sean C., Famuyide, Abimbola O., Kipp, Benjamin R., Halling, Kevin C., Yadav, Siddhartha, Couch, Fergus J., Podratz, Karl C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9714733/
https://www.ncbi.nlm.nih.gov/pubmed/36454788
http://dx.doi.org/10.1371/journal.pone.0278408

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