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Cell-free DNA topology depends on its subcellular and cellular origins in cancer

Cancer cells release large quantities of cell-free DNA (cfDNA) into the surrounding tissue and circulation. As cfDNA is a common source of biomarkers for liquid biopsy and has been implicated as a functional mediator for intercellular communication, fundamental characterization of cfDNA topology has...

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Detalles Bibliográficos
Autores principales: Malkin, Ethan Z., De Michino, Steven, Lambie, Meghan, Gill, Rita, Zhao, Zhen, Rostami, Ariana, Arruda, Andrea, Minden, Mark D., Bratman, Scott V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9714790/
https://www.ncbi.nlm.nih.gov/pubmed/36125881
http://dx.doi.org/10.1172/jci.insight.159590