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Cell-free DNA topology depends on its subcellular and cellular origins in cancer
Cancer cells release large quantities of cell-free DNA (cfDNA) into the surrounding tissue and circulation. As cfDNA is a common source of biomarkers for liquid biopsy and has been implicated as a functional mediator for intercellular communication, fundamental characterization of cfDNA topology has...
Autores principales: | Malkin, Ethan Z., De Michino, Steven, Lambie, Meghan, Gill, Rita, Zhao, Zhen, Rostami, Ariana, Arruda, Andrea, Minden, Mark D., Bratman, Scott V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9714790/ https://www.ncbi.nlm.nih.gov/pubmed/36125881 http://dx.doi.org/10.1172/jci.insight.159590 |
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