Successful prednisolone or calcimimetic treatment of acquired hypocalciuric hypercalcemia caused by biased allosteric CaSR autoantibodies

Biased agonism is a frontier field in GPCR research. Acquired hypocalciuric hypercalcemia (AHH) is a rare disease caused by calcium-sensing receptor (CaSR) autoantibodies, to date, showing either simple blocking or biased properties (i.e., stimulatory or blocking effects on different downstream sign...

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Detalles Bibliográficos
Autores principales: Makita, Noriko, Sato, Junichiro, Manaka, Katsunori, Akahane, Kimiko, Ito, Takahiro, Yamazaki, Hajime, Mizoguchi, Akira, Hikima, Yusuke, Horikoshi, Hirofumi, Nangaku, Masaomi, Iiri, Taroh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9714797/
https://www.ncbi.nlm.nih.gov/pubmed/36099030
http://dx.doi.org/10.1172/jci.insight.156742

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