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Patient-derived three-dimensional cortical neurospheres to model Parkinson’s disease
There are currently no preventive or disease-modifying therapies for Parkinson’s Disease (PD). Failures in clinical trials necessitate a re-evaluation of existing pre-clinical models in order to adopt systems that better recapitulate underlying disease mechanisms and better predict clinical outcomes...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9714816/ https://www.ncbi.nlm.nih.gov/pubmed/36454869 http://dx.doi.org/10.1371/journal.pone.0277532 |