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Patient-derived three-dimensional cortical neurospheres to model Parkinson’s disease

There are currently no preventive or disease-modifying therapies for Parkinson’s Disease (PD). Failures in clinical trials necessitate a re-evaluation of existing pre-clinical models in order to adopt systems that better recapitulate underlying disease mechanisms and better predict clinical outcomes...

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Detalles Bibliográficos
Autores principales:	Raja, Waseem K., Neves, Esther, Burke, Christopher, Jiang, Xin, Xu, Ping, Rhodes, Kenneth J., Khurana, Vikram, Scannevin, Robert H., Chung, Chee Yeun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9714816/ https://www.ncbi.nlm.nih.gov/pubmed/36454869 http://dx.doi.org/10.1371/journal.pone.0277532

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