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Centrally expressed Cav3.2 T-type calcium channel is critical for the initiation and maintenance of neuropathic pain

Cav3.2 T-type calcium channel is a major molecular actor of neuropathic pain in peripheral sensory neurons, but its involvement at the supraspinal level is almost unknown. In the anterior pretectum (APT), a hub of connectivity of the somatosensory system involved in pain perception, we show that Cav...

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Detalles Bibliográficos
Autores principales: Fayad, Sophie L, Ourties, Guillaume, Le Gac, Benjamin, Jouffre, Baptiste, Lamoine, Sylvain, Fruquière, Antoine, Laffray, Sophie, Gasmi, Laila, Cauli, Bruno, Mallet, Christophe, Bourinet, Emmanuel, Bessaih, Thomas, Lambert, Régis C, Leresche, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9714965/
https://www.ncbi.nlm.nih.gov/pubmed/36416409
http://dx.doi.org/10.7554/eLife.79018