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Kiaa1024L/Minar2 is essential for hearing by regulating cholesterol distribution in hair bundles

Unbiased genetic screens implicated a number of uncharacterized genes in hearing loss, suggesting some biological processes required for auditory function remain unexplored. Loss of Kiaa1024L/Minar2, a previously understudied gene, caused deafness in mice, but how it functioned in the hearing was un...

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Detalles Bibliográficos
Autores principales: Gao, Ge, Guo, Shuyu, Zhang, Quan, Zhang, Hefei, Zhang, Cuizhen, Peng, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9714970/
https://www.ncbi.nlm.nih.gov/pubmed/36317962
http://dx.doi.org/10.7554/eLife.80865