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Impact of the early phase of COVID-19 on the trends of isolated bacteria in the national database of Japan: an interrupted time-series analysis
OBJECTIVES: During the coronavirus disease 2019 (COVID-19) pandemic, a change in the trend of infections was observed. However, there are few reports comprehensively assessing the impact of the early phase of COVID-19 on the trend of bacteria isolated. METHODS: We extracted the number of positive cu...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The British Infection Association. Published by Elsevier Ltd.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9715262/ https://www.ncbi.nlm.nih.gov/pubmed/36463984 http://dx.doi.org/10.1016/j.jinf.2022.11.025 |
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author | Kakimoto, Masaki Miyamori, Daisuke Omori, Keitaro Kobayashi, Tomoki Ikeda, Kotaro Kashiyama, Seiya Ohge, Hiroki Ito, Masanori |
author_facet | Kakimoto, Masaki Miyamori, Daisuke Omori, Keitaro Kobayashi, Tomoki Ikeda, Kotaro Kashiyama, Seiya Ohge, Hiroki Ito, Masanori |
author_sort | Kakimoto, Masaki |
collection | PubMed |
description | OBJECTIVES: During the coronavirus disease 2019 (COVID-19) pandemic, a change in the trend of infections was observed. However, there are few reports comprehensively assessing the impact of the early phase of COVID-19 on the trend of bacteria isolated. METHODS: We extracted the number of positive cultures of hospitalized patients for approximately 200 institutions using the Japanese national database. The outcome was the ratio of 10 species isolated in comparison to the total isolates for each month. Interrupted time-series analyses were conducted between 13 (from Jan-2019 to Jan-2020) and 8 (from May-2020 to Dec-2020) monthly data points. RESULTS: A total of 369,210 isolates were involved. Differences in the level change for Streptococcus pneumoniae, Haemophilus influenzae, and Streptococcus pyogenes decreased significantly by 0.272 (95% confidence interval [CI]:0.192-0.352), 0.244 (95%CI:0.174-0.314), and 0.324 (95%CI:0.06-0.589), respectively. Bacteria transmitted by contact infection, such as Staphylococcus aureus, did not decrease. Differences in slope change were not significant in all species. CONCLUSIONS: The ratios of isolated bacteria transmitted by droplet infection decreased immediately after the early phase of COVID-19 and maintained the same level. The awareness and behavioral changes toward increased COVID-19 prevention might have a substantial impact on the prevention of bacterial infections, especially droplet infections. |
format | Online Article Text |
id | pubmed-9715262 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | The British Infection Association. Published by Elsevier Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-97152622022-12-02 Impact of the early phase of COVID-19 on the trends of isolated bacteria in the national database of Japan: an interrupted time-series analysis Kakimoto, Masaki Miyamori, Daisuke Omori, Keitaro Kobayashi, Tomoki Ikeda, Kotaro Kashiyama, Seiya Ohge, Hiroki Ito, Masanori J Infect Article OBJECTIVES: During the coronavirus disease 2019 (COVID-19) pandemic, a change in the trend of infections was observed. However, there are few reports comprehensively assessing the impact of the early phase of COVID-19 on the trend of bacteria isolated. METHODS: We extracted the number of positive cultures of hospitalized patients for approximately 200 institutions using the Japanese national database. The outcome was the ratio of 10 species isolated in comparison to the total isolates for each month. Interrupted time-series analyses were conducted between 13 (from Jan-2019 to Jan-2020) and 8 (from May-2020 to Dec-2020) monthly data points. RESULTS: A total of 369,210 isolates were involved. Differences in the level change for Streptococcus pneumoniae, Haemophilus influenzae, and Streptococcus pyogenes decreased significantly by 0.272 (95% confidence interval [CI]:0.192-0.352), 0.244 (95%CI:0.174-0.314), and 0.324 (95%CI:0.06-0.589), respectively. Bacteria transmitted by contact infection, such as Staphylococcus aureus, did not decrease. Differences in slope change were not significant in all species. CONCLUSIONS: The ratios of isolated bacteria transmitted by droplet infection decreased immediately after the early phase of COVID-19 and maintained the same level. The awareness and behavioral changes toward increased COVID-19 prevention might have a substantial impact on the prevention of bacterial infections, especially droplet infections. The British Infection Association. Published by Elsevier Ltd. 2023-02 2022-12-02 /pmc/articles/PMC9715262/ /pubmed/36463984 http://dx.doi.org/10.1016/j.jinf.2022.11.025 Text en © 2022 The British Infection Association. Published by Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Kakimoto, Masaki Miyamori, Daisuke Omori, Keitaro Kobayashi, Tomoki Ikeda, Kotaro Kashiyama, Seiya Ohge, Hiroki Ito, Masanori Impact of the early phase of COVID-19 on the trends of isolated bacteria in the national database of Japan: an interrupted time-series analysis |
title | Impact of the early phase of COVID-19 on the trends of isolated bacteria in the national database of Japan: an interrupted time-series analysis |
title_full | Impact of the early phase of COVID-19 on the trends of isolated bacteria in the national database of Japan: an interrupted time-series analysis |
title_fullStr | Impact of the early phase of COVID-19 on the trends of isolated bacteria in the national database of Japan: an interrupted time-series analysis |
title_full_unstemmed | Impact of the early phase of COVID-19 on the trends of isolated bacteria in the national database of Japan: an interrupted time-series analysis |
title_short | Impact of the early phase of COVID-19 on the trends of isolated bacteria in the national database of Japan: an interrupted time-series analysis |
title_sort | impact of the early phase of covid-19 on the trends of isolated bacteria in the national database of japan: an interrupted time-series analysis |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9715262/ https://www.ncbi.nlm.nih.gov/pubmed/36463984 http://dx.doi.org/10.1016/j.jinf.2022.11.025 |
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