Altered and allele-specific open chromatin landscape reveals epigenetic and genetic regulators of innate immunity in COVID-19

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection causes severe COVID-19 in some patients and mild COVID-19 in others. Dysfunctional innate immune responses have been identified to contribute to COVID-19 severity, but the key regulators are still unknown. Here, we present an int...

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Detalles Bibliográficos
Autores principales: Zhang, Bowen, Zhang, Zhenhua, Koeken, Valerie A.C.M., Kumar, Saumya, Aillaud, Michelle, Tsay, Hsin-Chieh, Liu, Zhaoli, Kraft, Anke R.M., Soon, Chai Fen, Odak, Ivan, Bošnjak, Berislav, Vlot, Anna, Swertz, Morris A., Ohler, Uwe, Geffers, Robert, Illig, Thomas, Huehn, Jochen, Saliba, Antoine-Emmanuel, Sander, Leif Erik, Förster, Reinhold, Xu, Cheng-Jian, Cornberg, Markus, Schulte, Leon N., Li, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9715265/
https://www.ncbi.nlm.nih.gov/pubmed/36474914
http://dx.doi.org/10.1016/j.xgen.2022.100232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9715265/
https://www.ncbi.nlm.nih.gov/pubmed/36474914
http://dx.doi.org/10.1016/j.xgen.2022.100232

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