Deferiprone−Resveratrol Hybrid, an Iron-Chelating Compound, Acts as an Antimalarial and Hepatoprotective Agent in Plasmodium berghei-Infected Mice

Free heme in plasma acts as a prooxidant; thus, it is bound to hemopexin and eliminated by the liver. High iron content in the liver can support Plasmodium growth and cause oxidative liver injury. Inversely, the withholding of excessive iron can inhibit this growth and protect the liver against mala...

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Detalles Bibliográficos
Autores principales: Chuljerm, Hataichanok, Maneekesorn, Supawadee, Punsawad, Chuchard, Somsak, Voravuth, Ma, Yongmin, Ruangsuriya, Jetsada, Srichairatanakool, Somdet, Koonyosying, Pimpisid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9715320/
https://www.ncbi.nlm.nih.gov/pubmed/36466999
http://dx.doi.org/10.1155/2022/3869337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9715320/
https://www.ncbi.nlm.nih.gov/pubmed/36466999
http://dx.doi.org/10.1155/2022/3869337

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