Activation of the pattern recognition receptor NOD1 in periodontitis impairs the osteogenic capacity of human periodontal ligament stem cells via p38/MAPK signalling

OBJECTIVES: Nucleotide oligomerization domain receptor 1 (NOD1) mediates host recognition of pathogenic bacteria in periodontium. However, the specific role of NOD1 in regulating osteogenesis is unclear. Therefore, this study focused on the activation status of NOD1 in periodontitis and its effect o...

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Detalles Bibliográficos
Autores principales: He, Yuying, Wu, Zuping, Chen, Sirui, Wang, Jiahe, Zhu, Li, Xie, Jing, Zhou, Chenchen, Zou, Shujuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9715354/
https://www.ncbi.nlm.nih.gov/pubmed/36043447
http://dx.doi.org/10.1111/cpr.13330

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