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Phase I-metabolism studies of the synthetic cannabinoids PX-1 and PX-2 using three different in vitro models
PURPOSE: Synthetic cannabinoids (SCs), highly metabolized substances, are rarely found unmodified in urine samples. Urine screening relies on SC metabolite detection, requiring metabolism knowledge. Metabolism data can be acquired via in vitro assays, e.g., human hepatocytes, pooled human liver micr...
Autores principales: | Dahm, Patrick, Thomas, Andreas, Rothschild, Markus A., Thevis, Mario, Mercer-Chalmers-Bender, Katja |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Nature Singapore
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9715525/ https://www.ncbi.nlm.nih.gov/pubmed/36454402 http://dx.doi.org/10.1007/s11419-021-00606-6 |
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