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Qualitative analysis of 7- and 8-hydroxyzolpidem and discovery of novel zolpidem metabolites in postmortem urine using liquid chromatography–tandem mass spectrometry

PURPOSE: Zolpidem (ZOL) is a hypnotic sometimes used in drug-facilitated crimes. Understanding ZOL metabolism is important for proving ZOL intake. In this study, we synthesized standards of hydroxyzolpidems with a hydroxy group attached to the pyridine ring and analyzed them to prove their presence...

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Detalles Bibliográficos
Autores principales:	Yamaguchi, Koji, Miyaguchi, Hajime, Ohno, Youkichi, Kanawaku, Yoshimasa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Nature Singapore 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9715527/ https://www.ncbi.nlm.nih.gov/pubmed/36454403 http://dx.doi.org/10.1007/s11419-021-00611-9

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