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A 3D-printed surgical guide for ischemic scar targeting and ablation

BACKGROUND: 3D printing technology development in medical fields allows to create 3D models to assist preoperative planning and support surgical procedures. Cardiac ischemic scar is clinically associated with malignant arrhythmias. Catheter ablation is aimed at eliminating the arrhythmogenic tissue...

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Autores principales: Candelari, Mara, Cappello, Ida Anna, Pannone, Luigi, Monaco, Cinzia, Talevi, Giacomo, Bori, Edoardo, Ramak, Robbert, La Meir, Mark, Gharaviri, Ali, Chierchia, Gian Battista, Innocenti, Bernardo, de Asmundis, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9715585/
https://www.ncbi.nlm.nih.gov/pubmed/36465435
http://dx.doi.org/10.3389/fcvm.2022.1029816
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author Candelari, Mara
Cappello, Ida Anna
Pannone, Luigi
Monaco, Cinzia
Talevi, Giacomo
Bori, Edoardo
Ramak, Robbert
La Meir, Mark
Gharaviri, Ali
Chierchia, Gian Battista
Innocenti, Bernardo
de Asmundis, Carlo
author_facet Candelari, Mara
Cappello, Ida Anna
Pannone, Luigi
Monaco, Cinzia
Talevi, Giacomo
Bori, Edoardo
Ramak, Robbert
La Meir, Mark
Gharaviri, Ali
Chierchia, Gian Battista
Innocenti, Bernardo
de Asmundis, Carlo
author_sort Candelari, Mara
collection PubMed
description BACKGROUND: 3D printing technology development in medical fields allows to create 3D models to assist preoperative planning and support surgical procedures. Cardiac ischemic scar is clinically associated with malignant arrhythmias. Catheter ablation is aimed at eliminating the arrhythmogenic tissue until the sinus rhythm is restored. The scope of this work is to describe the workflow for a 3D surgical guide able to define the ischemic scar and target catheter ablation. MATERIALS AND METHODS: For the patient-specific 3D surgical guide and 3D heart phantom model realization, both CT scan and cardiac MRI images were processed; this was necessary to extract anatomical structures and pathological information, respectively. Medical images were uploaded and processed in 3D Slicer. For the surgical guide modeling, images from CT scan and MRI were loaded in Meshmixer and merged. For the heart phantom realization, only the CT segmentation was loaded in Meshmixer. The surgical guide was printed in MED625FLX with Polyjet technology. The heart phantom was printed in polylactide with FDM technology. RESULTS: 3D-printed surgical model was in agreement with prespecified imputed measurements. The phantom fitting test showed high accuracy of the 3D surgical tool compared with the patient-specific reproduced heart. Anatomical references in the surgical guide ensured good stability. Ablation catheter fitting test showed high suitability of the guide for different ablation tools. CONCLUSION: A 3D-printed guide for ventricular tachycardia ablation is feasible and accurate in terms of measurements, stability, and geometrical structure. Concerning clinical use, further clinical investigations are eagerly awaited.
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spelling pubmed-97155852022-12-03 A 3D-printed surgical guide for ischemic scar targeting and ablation Candelari, Mara Cappello, Ida Anna Pannone, Luigi Monaco, Cinzia Talevi, Giacomo Bori, Edoardo Ramak, Robbert La Meir, Mark Gharaviri, Ali Chierchia, Gian Battista Innocenti, Bernardo de Asmundis, Carlo Front Cardiovasc Med Cardiovascular Medicine BACKGROUND: 3D printing technology development in medical fields allows to create 3D models to assist preoperative planning and support surgical procedures. Cardiac ischemic scar is clinically associated with malignant arrhythmias. Catheter ablation is aimed at eliminating the arrhythmogenic tissue until the sinus rhythm is restored. The scope of this work is to describe the workflow for a 3D surgical guide able to define the ischemic scar and target catheter ablation. MATERIALS AND METHODS: For the patient-specific 3D surgical guide and 3D heart phantom model realization, both CT scan and cardiac MRI images were processed; this was necessary to extract anatomical structures and pathological information, respectively. Medical images were uploaded and processed in 3D Slicer. For the surgical guide modeling, images from CT scan and MRI were loaded in Meshmixer and merged. For the heart phantom realization, only the CT segmentation was loaded in Meshmixer. The surgical guide was printed in MED625FLX with Polyjet technology. The heart phantom was printed in polylactide with FDM technology. RESULTS: 3D-printed surgical model was in agreement with prespecified imputed measurements. The phantom fitting test showed high accuracy of the 3D surgical tool compared with the patient-specific reproduced heart. Anatomical references in the surgical guide ensured good stability. Ablation catheter fitting test showed high suitability of the guide for different ablation tools. CONCLUSION: A 3D-printed guide for ventricular tachycardia ablation is feasible and accurate in terms of measurements, stability, and geometrical structure. Concerning clinical use, further clinical investigations are eagerly awaited. Frontiers Media S.A. 2022-11-18 /pmc/articles/PMC9715585/ /pubmed/36465435 http://dx.doi.org/10.3389/fcvm.2022.1029816 Text en Copyright © 2022 Candelari, Cappello, Pannone, Monaco, Talevi, Bori, Ramak, La Meir, Gharaviri, Chierchia, Innocenti and de Asmundis. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cardiovascular Medicine
Candelari, Mara
Cappello, Ida Anna
Pannone, Luigi
Monaco, Cinzia
Talevi, Giacomo
Bori, Edoardo
Ramak, Robbert
La Meir, Mark
Gharaviri, Ali
Chierchia, Gian Battista
Innocenti, Bernardo
de Asmundis, Carlo
A 3D-printed surgical guide for ischemic scar targeting and ablation
title A 3D-printed surgical guide for ischemic scar targeting and ablation
title_full A 3D-printed surgical guide for ischemic scar targeting and ablation
title_fullStr A 3D-printed surgical guide for ischemic scar targeting and ablation
title_full_unstemmed A 3D-printed surgical guide for ischemic scar targeting and ablation
title_short A 3D-printed surgical guide for ischemic scar targeting and ablation
title_sort 3d-printed surgical guide for ischemic scar targeting and ablation
topic Cardiovascular Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9715585/
https://www.ncbi.nlm.nih.gov/pubmed/36465435
http://dx.doi.org/10.3389/fcvm.2022.1029816
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