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Design of human immunodeficiency virus-1 neutralizing peptides targeting CD4-binding site: An integrative computational biologics approach

Peptide therapeutics have recently gained momentum in antiviral therapy due to their increased potency and cost-effectiveness. Interaction of the HIV-1 envelope gp120 with the host CD4 receptor is a critical step for viral entry, and therefore the CD4-binding site (CD4bs) of gp120 is a potential hot...

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Detalles Bibliográficos
Autores principales:	Vivekanandan, Sandhya, Vetrivel, Umashankar, Hanna, Luke Elizabeth
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9715589/ https://www.ncbi.nlm.nih.gov/pubmed/36465923 http://dx.doi.org/10.3389/fmed.2022.1036874

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